D E P A R T M E N T S:

DISCOVERY!:

Roy C. Page: Leader in Collaborative and Multidisciplinary Research in Periodontology

S. Bordin, A.S. Narayanan, and P.B. Robertson
The authors pay tribute to Roy Page’s unique and transforming research contributions to the understanding of the pathogenesis and clinical management of the periodontal diseases.

J Dent Res 2008 87: 293-295. [Full Text] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Degenerative Disorders of the Temporomandibular Joint: Etiology, Diagnosis, and Treatment

E. Tanaka, M.S. Detamore, and L.G. Mercuri
The authors review etiologies that involve biomechanical and biochemical factors associated with functional overloading of the temporomandibular joint and the clinical, radiographic, and biochemical findings important in the diagnosis of TMJ-osteoarthrosis, as well as non-invasive and invasive modalities in its management and the possibility of tissue engineering.

J Dent Res 2008 87: 296-307. [Abstract] [Full Text] [Figures Only] [PDF]  

Oral Manifestations of Sjögren’s Syndrome

S.A. Mathews, B.T. Kurien, and R.H. Scofield
This article specifically addresses the presence of dental caries and other oral problems associated with Sjögren’s syndrome.

J Dent Res 2008 87: 308-318. [Abstract] [Full Text] [PDF]  

RAPID COMMUNICATION:

Serum Levels of Resistin and Adiponectin in Women with Periodontitis: the Hisayama Study

T. Saito, N. Yamaguchi, Y. Shimazaki, H. Hayashida, K. Yonemoto, Y. Doi, Y. Kiyohara, M. Iida, and Y. Yamashita
An increased serum resistin level in middle-aged women with periodontitis may affect systemic health.

J Dent Res 2008 87: 319-322. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Osteoporosis and Oral Infection: Independent Risk Factors for Oral Bone Loss

R.M. Brennan-Calanan, R.J. Genco, G.E. Wilding, K.M. Hovey, M. Trevisan, and J. Wactawski-Wende
This is the first report evaluating the joint associations among oral bacteria, osteoporosis, and alveolar crestal height.

J Dent Res 2008 87: 323-327. [Abstract] [Full Text] [PDF]  

Periodontal Pathogens and Gestational Diabetes Mellitus

A.P. Dasanayake, N. Chhun, A.C.R. Tanner, R.G. Craig, M.J. Lee, A.F. Moore, and R.G. Norman
The presence of Tannerella forsythia in vaginal flora is a potential risk factor for gestational diabetes mellitus.

J Dent Res 2008 87: 328-333. [Abstract] [Full Text] [PDF]  

Oral Health and Mortality Risk from Pneumonia in the Elderly

S. Awano, T. Ansai, Y. Takata, I. Soh, S. Akifusa, T. Hamasaki, A. Yoshida, K. Sonoki, K. Fujisawa, and T. Takehara
This is the first study to show that periodontal disease in the elderly is associated with mortality from pneumonia.

J Dent Res 2008 87: 334-339. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Optimal Drinking Water Composition for Caries Control in Populations

M. Bruvo, K. Ekstrand, E. Arvin, H. Spliid, D. Moe, S. Kirkeby, and A. Bardow
This is the first time a mathematical model with two ions (calcium and fluoride) has been developed for the effect of drinking water on DMF-S, and can be used for the design of optimal drinking water for caries control in populations.

J Dent Res 2008 87: 340-343. [Abstract] [Full Text] [Figures Only] [PDF]  

Fluoride and Casein Phosphopeptide-Amorphous Calcium Phosphate

E.C. Reynolds, F. Cai, N.J. Cochrane, P. Shen, G.D. Walker, M.V. Morgan, and C. Reynolds
The addition of 2% casein phosphopeptide-amorphous calcium phosphate to a 450-ppm-F mouthrinse significantly increased the incorporation of fluoride into plaque.

J Dent Res 2008 87: 344-348. [Abstract] [Full Text] [Figures Only] [PDF]  

Treatment of Health Complaints Attributed to Amalgam

D. Melchart, S. Vogt, W. Köhler, A. Streng, W. Weidenhammer, L. Kremers, R. Hickel, N. Felgenhauer, T. Zilker, E. Wühr, and S. Halbach
This is the first comparative randomized controlled trial of treatment strategies for adults with amalgam restorations.

J Dent Res 2008 87: 349-353. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

DLX3 Mutation in a New Family and Its Phenotypic Variations

S.-K. Lee, Z.H. Lee, S.-J. Lee, B.-D. Ahn, Y.-J. Kim, S.-H. Lee, and J.-W. Kim
The authors have identified a gene mutation with not only enamel defects, but also other clinical phenotypes resembling those of tricho-dento-osseous syndrome.

J Dent Res 2008 87: 354-357. [Abstract] [Full Text] [Figures Only] [PDF]  

Cortical Representation Area of Human Dental Pulp

K. Kubo, Y. Shibukawa, M. Shintani, T. Suzuki, T. Ichinohe, and Y. Kaneko
The authors provide a detailed organizational map of the orofacial area in the primary somatosensory cortex, by adding dental pulp to the classic "sensory homunculus".

J Dent Res 2008 87: 358-362. [Abstract] [Full Text] [Figures Only] [PDF]  

Biomaterials & Bioengineering:

Veneer vs. Core Failure in Adhesively Bonded All-ceramic Crown Layers

J.J.-W. Lee, J.-Y. Kwon, S. Bhowmick, I.K. Lloyd, E.D. Rekow, and B.R. Lawn
The authors found no significant differences in critical loads for veneer cracking in specimens containing alumina or zirconia cores.

J Dent Res 2008 87: 363-366. [Abstract] [Full Text] [Figures Only] [PDF]  

Contraction Stress Determinants in Dimethacrylate Composites

F. Gonçalves, C.S. Pfeifer, J.L. Ferracane, and R.R. Braga
In composites with the same inorganic content, the composition of the organic matrix plays an important role in determining the polymerization stress as a direct result of the influence on conversion and, in turn, on shrinkage and elastic modulus.

J Dent Res 2008 87: 367-371. [Abstract] [Full Text] [Figures Only] [PDF]  

N-acetyl Cysteine (NAC)-assisted Detoxification of PMMA Resin

M. Yamada, N. Kojima, A. Paranjpe, W. Att, H. Aita, A. Jewett, and T. Ogawa
N-acetyl cysteine, an anti-oxidant amino acid, has the potential to detoxify PMMA resins and significantly restore the odontoblast-like cell phenotype.

J Dent Res 2008 87: 372-377. [Abstract] [Full Text] [Figures Only] [PDF]  

Distribution and Excretion of BisGMA in Guinea Pigs

F.X. Reichl, M. Seiss, N. Kleinsasser, K. Kehe, K.H. Kunzelmann, P. Thomas, W. Spahl, and R. Hickel
BisGMA does not reach cytotoxic levels in mammalian tissues.

J Dent Res 2008 87: 378-380. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Nano-mechanical Properties of Fluoride-treated Enamel Surfaces

Y.-R. Jeng, T.-T. Lin, T.-Y. Wong, H.-J. Chang, and D.-B. Shieh
The authors confirm the long-term effectiveness of topical fluoride treatment.

J Dent Res 2008 87: 381-385. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biological:

Mesenchyme is Responsible for Tooth Suppression in the Mouse Lower Diastema

G.H. Yuan, L. Zhang, Y.D. Zhang, M.W. Fan, Z. Bian, and Z. Chen
This is the first report of the odontogenic capabilities of E11.5 lower diastemal epithelium and mesenchyme.

J Dent Res 2008 87: 386-390. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Role of NBCe1 and AE2 in Secretory Ameloblasts

M.L. Paine, M.L. Snead, H.J. Wang, N. Abuladze, A. Pushkin, W. Liu, L.Y. Kao, S.M. Wall, Y.-H. Kim, and I. Kurtz
The authors provide the first evidence that AE2 and NBCe1 are expressed in ameloblasts in vivo in a polarized fashion, thereby providing a mechanism for ameloblast transcellular bicarbonate secretion in the process of enamel formation and maturation.

J Dent Res 2008 87: 391-395. [Abstract] [Full Text] [Figures Only] [PDF]  

An Anti-c-Fms Antibody Inhibits Orthodontic Tooth Movement

H. Kitaura, M. Yoshimatsu, Y. Fujimura, T. Eguchi, H. Kohara, A. Yamaguchi, and N. Yoshida
Macrophage colony-stimulating factor plays an important role in mechanical loading-induced osteoclastogenesis and bone resorption during orthodontic tooth movement mediated by TNF-.

J Dent Res 2008 87: 396-400. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Luteolin Induces Apoptosis in Oral Squamous Cancer Cells

S.-F. Yang, W.-E. Yang, H.-R. Chang, S.-C. Chu, and Y.-S. Hsieh
This is the first report on the tumor-suppressive function of luteolin in oral cancer cells via inducing apoptosis and cell-cycle arrest.

J Dent Res 2008 87: 401-406. [Abstract] [Full Text] [Figures Only] [PDF]  

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