D E P A R T M E N T S:

DISCOVERY!:

The National Student Research Group of the AADR—An Introduction

James M. Rogér, Julie A. Javarone, Erin L. Ealba, Michael R. Markiewicz, and Anthony B. Morlandt
The authors introduce and describe the missions and goals, recent activities, and future initiatives of the National Student Research Group of the AADR.

J Dent Res 2007 86: 388-391. [Abstract] [Full Text] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Hereditary Dentin Defects

J.-W. Kim and J.P. Simmer
The authors discuss the development of the dentin extracellular matrix in the context of its evolution, and discuss the phenotypes and clinical classifications of isolated hereditary defects of tooth dentin in the context of recent genetic data respecting their genetic etiologies.

J Dent Res 2007 86: 392-399. [Abstract] [Full Text] [Figures Only] [PDF] Appendix  

Obesity, Inflammation, and Periodontal Disease

N. Pischon, N. Heng, J.-P. Bernimoulin, B.-M. Kleber, S.N. Willich, and T. Pischon
The authors provide an overview of the definition and assessment of obesity and related chronic diseases and complications that may be important in the periodontist’s office.

J Dent Res 2007 86: 400-409. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Effectiveness of Fluoride in Preventing Caries in Adults

S.O. Griffin, E. Regnier, P.M. Griffin, and V. Huntley
Fluoride prevents caries in adults of all ages.

J Dent Res 2007 86: 410-415. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Gene Polymorphisms and the Prevalence of Key Periodontal Pathogens

L. Nibali, D.R. Ready, M. Parkar, P.M. Brett, M. Wilson, M.S. Tonetti, and G.S. Griffiths
Complex interactions between the microbiota and the host genome may be the basis of susceptibility to aggressive periodontitis.

J Dent Res 2007 86: 416-420. [Abstract] [Full Text] [PDF]  

Sequence of Oral Bacterial Co-adhesion and Non-contact Brushing

H.C. van der Mei, M. Rustema-Abbing, G.M. Bruinsma, B. Gottenbos, and H.J. Busscher
At contact, rotary and sonic brushing performed equally well in bacterial removal, while at 4 mm both lost some efficacy.

J Dent Res 2007 86: 421-425. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biomaterials & Bioengineering:

Self-assembling Peptide Scaffolds Promote Enamel Remineralization

J. Kirkham, A. Firth, D. Vernals, N. Boden, C. Robinson, R.C. Shore, S.J. Brookes, and A. Aggeli
Self-assembling peptides may be useful in the modulation of mineral behavior during in situ dental tissue engineering.

J Dent Res 2007 86: 426-430. [Abstract] [Full Text] [Figures Only] [PDF]  

Protection Offered by Root-surface Restorative Materials against Biofilm Challenge

H.K. Yip, J. Guo, and W.H.S. Wong
Glass-ionomer restoratives conferred a preventive effect on root surfaces against initial cariogenic challenge with mixed-species oral biofilm without therapeutic intervention.

J Dent Res 2007 86: 431-435. [Abstract] [Full Text] [Figures Only] [PDF]  

Zymographic Analysis and Characterization of MMP-2 and -9 Forms in Human Sound Dentin

A. Mazzoni, F. Mannello, F.R. Tay, G.A.M. Tonti, S. Papa, G. Mazzotti, R. Di Lenarda, D.H. Pashley, and L. Breschi
Using new acidic demineralization and enhanced protein recovery procedures, the authors identified, for the first time, several gelatinolytic matrix metalloproteinases in human dentin matrix, as well as several forms of both zymogen and activated MMP-9 in dentin extracts.

J Dent Res 2007 86: 436-440. [Abstract] [Full Text] [Figures Only] [PDF]  

In vitro Evaluation of Corrosion and Cytotoxicity of Orthodontic Brackets

M.T. Costa, M.A. Lenza, C.S. Gosch, I. Costa, and F. Ribeiro-Dias
Low-nickel stainless steel presents better in vitro biocompatibility than AISI 304 stainless steel brackets.

J Dent Res 2007 86: 441-445. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biological:

Arg-gingipain A DNA Vaccine Prevents Alveolar Bone Loss in Mice

K. Miyachi, K. Ishihara, R. Kimizuka, and K. Okuda
The authors describe a new approach to the clinical prevention of periodontal disease using a combination of rgpA DNA vaccine and the HVJ envelope vector system.

J Dent Res 2007 86: 446-450. [Abstract] [Full Text] [Figures Only] [PDF]  

Effect of Aqueous Ozone on the NF-B System

K.C. Huth, B. Saugel, F.M. Jakob, C. Cappello, M. Quirling, E. Paschos, K. Ern, R. Hickel, and K. Brand
The authors establish a condition under which aqueous ozone exerts inhibitory effects on the NF-B system, suggesting that it has an anti-inflammatory capacity.

J Dent Res 2007 86: 451-456. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Matrix Metalloproteinase-3 Differences in Oral and Skin Fibroblasts

S.T.W. McKeown, J.J. Barnes, P.L. Hyland, F.T. Lundy, M.J. Fray, and C.R. Irwin
Increased MMP-3 production by oral fibroblasts may underlie the differences in wound-healing outcome seen in skin and oral mucosa.

J Dent Res 2007 86: 457-462. [Abstract] [Full Text] [Figures Only] [PDF]  

Mouse Molar Dentin Size/Shape is Dependent on Growth Hormone Status

J.R. Smid, J.E. Rowland, W.G. Young, K.T. Coschigano, J.J. Kopchick, and M.J. Waters
This is the first morphometric study of dentin in mouse models either expressing a growth hormone transgene or lacking the expression of a growth hormone receptor gene.

J Dent Res 2007 86: 463-468. [Abstract] [Full Text] [Figures Only] [PDF]  

Hard Tissue Formation in Subcutaneously Transplanted Rat Dental Pulp

A. Hosoya, H. Nakamura, T. Ninomiya, K. Hoshi, K. Yoshiba, N. Yoshiba, M. Takahashi, T. Okabe, N. Sahara, H. Yamada, E. Kasahara, and H. Ozawa
Pulp cells are able to form mineralized hard tissue in the absence of dentinal growth factors.

J Dent Res 2007 86: 469-474. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Effects of COX-2 Inhibitor in Temporomandibular Joint Acute Inflammation

T.C.B. Schütz, M.L. Andersen, and S. Tufik
The authors suggest the involvement of cyclo-oxygenase-2 enzyme in acute inflammation of the TMJ, specifically in REM sleep.

J Dent Res 2007 86: 475-479. [Abstract] [Full Text] [Figures Only] [PDF]  

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