D E P A R T M E N T S:

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Protective and Destructive Immunity in the Periodontium: Part 1—Innate and Humoral Immunity and the Periodontium

Y.-T.A. Teng
The author reviews recent findings on the innate Toll-like receptor immune system and the periodontium, humoral Ig immunity, and osteo-immunology and the T-cell-mediated network, along with the microbial virulent factors or antigens identified and their association with periodontal immunity.

J Dent Res 2006 85: 198-208. [Abstract] [Full Text] [Figures Only] [PDF]  

Protective and Destructive Immunity in the Periodontium: Part 2—T-cell-mediated Immunity in the Periodontium

Y.-T.A. Teng
The author discusses the protective and destructive aspects of the T-cell-mediated adaptive immunity associated with the bacterial virulent factors or antigenic determinants during periodontal pathogenesis.

J Dent Res 2006 85: 209-219. [Abstract] [Full Text] [Figures Only] [PDF]  

ERRATUM:

ERRATUM

J Dent Res 2006 85: 287. [Full Text] [PDF]  

R E S E A R C H  R E P O R T S:

Biological:

Silibinin Inhibits Invasion of Oral Cancer Cells by Suppressing the MAPK Pathway

P.-N. Chen, Y.-S. Hsieh, C.-L. Chiang, H.-L. Chiou, S.-F. Yang, and S.-C. Chu
Silibinin could reduce the invasion and metastasis of tumor cells, which could be of value in the development of a potential cancer therapy.

J Dent Res 2006 85: 220-225. [Abstract] [Full Text] [Figures Only] [PDF]  

Immediate Erosive Potential of Cola Drinks and Orange Juices

T. Jensdottir, P. Holbrook, B. Nauntofte, C. Buchwald, and A. Bardow
The erosive potential of soft drinks within the first minutes of exposure is solely dependent on the pH of the drinks and is ten-fold higher in cola drinks than in orange juice; however, in cola drinks, human salivary proteins may reduce the erosive potential up to 50%.

J Dent Res 2006 85: 226-230. [Abstract] [Full Text] [Figures Only] [PDF]  

Interactive Forces between Co-aggregating and Non-co-aggregating Oral Bacterial Pairs

F. Postollec, W. Norde, J. de Vries, H.J. Busscher, and H.C. van der Mei
Co-aggregation and co-adhesion may be reversible processes under the dynamic conditions of the human oral cavity.

J Dent Res 2006 85: 231-234. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Anti-inflammatory Activity of a High-molecular-weight Cranberry Fraction on Macrophages Stimulated by Lipopolysaccharides from Periodontopathogens

C. Bodet, F. Chandad, and D. Grenier
Cranberry constituents may offer perspectives for the development of a new therapeutic approach to the prevention and treatment of periodontitis.

J Dent Res 2006 85: 235-239. [Abstract] [Full Text] [Figures Only]  

Compressive Force Induces Osteoblast Apoptosis via Caspase-8

Y. Goga, M. Chiba, Y. Shimizu, and H. Mitani
The in vitro application of compressive force can induce apoptosis in MG-63 cells through the activation of caspase-3 via the caspase-8 signaling cascade.

J Dent Res 2006 85: 240-244. [Abstract] [Full Text] [Figures Only] [PDF]  

Hypermethylation of CpGs in the Promoter of the COL1A1 Gene in the Aged Periodontal Ligament

T. Ohi, Y. Uehara, M. Takatsu, M. Watanabe, and T. Ono
The authors discuss the possible importance of DNA hypermethylation in the promoter region for the age-associated decrease of COL1A1 gene expression.

J Dent Res 2006 85: 245-250. [Abstract] [Full Text] [Figures Only] [PDF]  

Functional ₁-Adrenoceptor Subtypes in Human Submandibular Glands

Z. Huang, L.L. Wu, Y.Y. Zhang, Y. Gao, and G.Y. Yu
This is the first report of the expression, distribution, and function of ₁-adrenoceptor subtypes in human submandibular glands.

J Dent Res 2006 85: 251-256. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

How Do Factors at Different Stages of the Lifecourse Contribute to Oral-health-related Quality of Life in Middle Age for Men and Women?

J. Mason, M.S. Pearce, A.W.G. Walls, L. Parker, and J.G. Steele
Lifecourse influences on oral-health-related quality of life appear different for men and women, which may have implications for the effectiveness of public health interventions and health promotion.

J Dent Res 2006 85: 257-261. [Abstract] [Full Text] [Figures Only] [PDF]  

Carbonated Soft Drinks and Dental Caries in the Primary Dentition

W. Sohn, B.A. Burt, and M.R. Sowers
This is the first cluster analysis of fluid consumption patterns among children in the United States.

J Dent Res 2006 85: 262-266. [Abstract] [Full Text] [PDF]  

Novel MSX1 Frameshift Causes Autosomal-dominant Oligodontia

J.-W. Kim, J.P. Simmer, B.P.-J. Lin, and J.C.-C. Hu
The most distinguishing feature of MSX1-associated oligodontia is the absence of maxillary first bicuspids, while the most distinguishing feature of PAX9-associated oligodontia is the frequent absence of the maxillary and mandibular second molar.

J Dent Res 2006 85: 267-271. [Abstract] [Full Text] [Figures Only] [PDF]  

Biomaterials & Bioengineering:

The Strengthening Mechanism of Resin Cements on Porcelain Surfaces

G.J.P. Fleming, F.R. Maguire, G. Bhamra, F.M. Burke, and P.M. Marquis
Resin strength enhancement is independent of defect severity.

J Dent Res 2006 85: 272-276. [Abstract] [Full Text] [Figures Only] [PDF]  

Fracture Surface Analysis of Clinically Failed Fixed Partial Dentures

B. Taskonak, J.J. Mecholsky, Jr., and K.J. Anusavice
Fracture initiation sites are controlled primarily by contact damage.

J Dent Res 2006 85: 277-281. [Abstract] [Full Text] [Figures Only] [PDF]  

Evaluation of a Self-limiting Concept in Dentinal Caries Removal

N.R.F.A. Silva, R.M. Carvalho, L.F. Pegoraro, F.R. Tay, and V.P. Thompson
The authors discuss a self-limiting concept to caries removal that should go forward with modifications in bur composition/hardness to ensure the complete removal of infected tissue.

J Dent Res 2006 85: 282-286. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

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