D E P A R T M E N T S:

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Epithelial-Mesenchymal Transformation during Craniofacial Development

P. Kang and K.K.H. Svoboda
This review focuses on the regulation of epithelial-mesenchymal transformation during neural crest cell migration, and fusion of the secondary palate and the upper lip.

J Dent Res 2005 84: 678-690. [Abstract] [Full Text] [Figures Only] [PDF]  

The Adaptive Remodeling of Condylar Cartilage— A Transition from Chondrogenesis to Osteogenesis

G. Shen and M. Ali Darendeliler
This review clarifies the distinctive biological aspects of the condylar cartilage and explores its adaptive remodeling pathway by identifying the phenotypic response during the transition from chondrogenesis to osteogenesis.

J Dent Res 2005 84: 691-699. [Abstract] [Full Text] [Figures Only] [PDF]  

RAPID COMMUNICATION:

Fusobacterium nucleatum Apoptosis-inducing Outer Membrane Protein

C.W. Kaplan, R. Lux, T. Huynh, A. Jewett, W. Shi, and S. Kinder Haake
This is the first report of a genetically defined and phenotypically characterized mutation in F. nucleatum.

J Dent Res 2005 84: 700-704. [Abstract] [Full Text] [Figures Only] [PDF]  

Smokeless Tobacco and Severe Active Periodontal Disease, NHANES III

M.A. Fisher, G.W. Taylor, and K.R. Tilashalski
This is the first report of the association between smokeless tobacco use and severe active periodontal disease.

J Dent Res 2005 84: 705-710. [Abstract] [Full Text] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Tuftelin, Mutans Streptococci, and Dental Caries Susceptibility

R. L. Slayton, M.E. Cooper, and M.L. Marazita
This is one of the first studies to use a candidate gene approach to investigate host susceptibility to dental caries.

J Dent Res 2005 84: 711-714. [Abstract] [Full Text] [PDF] [Appendix]  

New Coronal Caries in Older Adults: Implications for Prevention

S.O. Griffin, P.M. Griffin, J.L. Swann, and N. Zlobin
The rates of new coronal caries in older adults are equal to or higher than those in children and indicate a need for caries-prevention services.

J Dent Res 2005 84: 715-720. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Efficacy of Silver Diamine Fluoride for Caries Reduction in Primary Teeth and First Permanent Molars of Schoolchildren: 36-month Clinical Trial

J.C. Llodra, A. Rodriguez, B. Ferrer, V. Menardia, T. Ramos, and M. Morato
This is the first controlled clinical trial evaluating the effectiveness of a silver diamine fluoride solution for caries reduction in first permanent molars in schoolchildren.

J Dent Res 2005 84: 721-724. [Abstract] [Full Text] [PDF]  

Biomaterials & Bioengineering:

Oxygen Inhibition in Dental Resins

M.A. Gauthier, I. Stangel, T.H. Ellis, and X.X. Zhu
Polymerization at temperatures above ~ 110°C eliminates oxygen inhibition.

J Dent Res 2005 84: 725-729. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Incompatibility of Oxalate Desensitizers with Acidic, Fluoride-containing Total-etch Adhesives

C.K.Y. Yiu, N.M. King, B.I. Suh, L.J. Sharp, R.M. Carvalho, D.H. Pashley, and F.R. Tay
Surface spherical globules may have interfered with hybridization of demineralized dentin with OB and PB resins and caused compromised bond strength.

J Dent Res 2005 84: 730-735. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

EDTA Treatment Improves Resin-Dentin Bonds’ Resistance to Degradation

R. Osorio, M.C.G. Erhardt, L.A.F. Pimenta, E. Osorio, and M. Toledano
The collagen network is better-preserved after EDTA demineralization.

J Dent Res 2005 84: 736-740. [Abstract] [Full Text] [Figures Only] [PDF]  

Chlorhexidine Arrests Subclinical Degradation of Dentin Hybrid Layers in vivo

J. Hebling, D.H. Pashley, L. Tjäderhane, and F.R. Tay
The use of chlorhexidine as a matrix metalloproteinase inhibitor resulted in the arrest of in vivo degradation of hybrid layers.

J Dent Res 2005 84: 741-746. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Cyclosporin A Specifically Affects Nuclear PLCß₁ in Immunodepressed Heart Transplant Patients with Gingival Overgrowth

A. Ruggeri, Jr., L. Montebugnoli, A. Matteucci, N. Zini, L. Solimando, D. Servidio, P. Suppa, M. Cadenaro, L. Cocco, and L. Breschi
The authors support the hypothesis of a multi-factorial origin of gingival overgrowth, including specific changes in the gingival tissues orchestrating fibroblastic hyper-responsiveness as a consequence of a long-term in vivo exposure to cyclosporin A.

J Dent Res 2005 84: 747-751. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Effects of a High-cholesterol Diet on Cell Behavior in Rat Periodontitis

T. Tomofuji, H. Kusano, T. Azuma, D. Ekuni, T. Yamamoto, and T. Watanabe
High dietary cholesterol can initiate and augment periodontitis in the rat periodontitis model.

J Dent Res 2005 84: 752-756. [Abstract] [Full Text] [Figures Only] [PDF]  

Distraction Osteogenesis May Promote Periodontal Bone Regeneration

J. Faber, R.B. Azevedo, and S.N. Báo
Periodontal bone distraction may be a new treatment alternative for periodontal defects.

J Dent Res 2005 84: 757-761. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Effect of NOS Inhibitor on Cytokine and COX2 Expression in Rat Pulpitis

N. Kawashima, H. Nakano-Kawanishi, N. Suzuki, M. Takagi, and H. Suda
Nitric oxide synthesis is related to the initiation of mediator production, and its down-regulation would contribute to the prevention of pro-inflammatory mediator synthesis.

J Dent Res 2005 84: 762-767. [Abstract] [Full Text] [Figures Only] [PDF]  

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