D E P A R T M E N T S:

LETTERS TO THE EDITOR:

SMOKELESS TOBACCO AND PERIODONTAL DISEASE

Brad Rodu, Philip Cole, Monica A. Fisher, George W. Taylor, and Ken R. Tilashalski
J Dent Res 2005 84: 1086-1087. [Full Text] [PDF]  

DIFFUSION COEFFICIENT OF FLUORIDE IN DENTAL PLAQUE

Philip S. Stewart, Colin Robinson, and Philip Watson
J Dent Res 2005 84: 1087-1088. [Full Text] [PDF]  

DISCOVERY!:

Discovering the Impact of Ronald Gibbons on Dental Research and Beyond

R.P. Ellen, W.J. Loesche, and D. Bratthall
The authors pay tribute to the role of Ronald Gibbons in and beyond the field of fundamental oral microbiology.

J Dent Res 2005 84: 1089-1092. [Full Text] [PDF]  

CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE:

Biological Approaches to Bone Regeneration by Gene Therapy

R.T. Franceschi
The author describes safe, effective approaches for bone regeneration to reverse bone loss caused by trauma, disease, and tumor resection.

J Dent Res 2005 84: 1093-1103. [Abstract] [Full Text] [Figures Only] [PDF]  

Immunomodulation with Enterotoxins for the Generation of Secretory Immunity or Tolerance: Applications for Oral Infections

G. Hajishengallis, S. Arce, C.M. Gockel, T.D. Connell, and M.W. Russell
The authors discuss recent strategies—especially the use of heat-labile enterotoxins—as adjuvants or as coupled delivery agents to overcome the inherent unresponsiveness or tolerance of mucosal immune tissues to non-replicating antigens, to elicit potent mucosal and systemic immune responses.

J Dent Res 2005 84: 1104-1116. [Abstract] [Full Text] [Figures Only] [PDF]  

Genes and Related Proteins Involved in Amelogenesis Imperfecta

G. Stephanopoulos, M.-E. Garefalaki, and K. Lyroudia
The authors focus on the candidate genes involved in amelogenesis imperfecta and the proteins derived from them, and review current knowledge on their structure, localization within the tissue, and correlation with the various types of this disorder.

J Dent Res 2005 84: 1117-1126. [Abstract] [Full Text] [Figures Only] [PDF]  

RAPID COMMUNICATION:

Amelotin—a Novel Secreted, Ameloblast-specific Protein

K. Iwasaki, E. Bajenova, E. Somogyi-Ganss, M. Miller, V. Nguyen, H. Nourkeyhani, Y. Gao, M. Wendel, and B. Ganss
Amelotin is a novel factor produced by ameloblasts that plays a critical role in the formation of dental enamel.

J Dent Res 2005 84: 1127-1132. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Clinical:

Low-fluoride Dentifrice and Gastrointestinal Fluoride Absorption after Meals

J.A. Cury, F.S. Del Fiol, L.M.A. Tenuta, and P.L. Rosalen
The risk of fluorosis could be reduced by the use of either a low-fluoride dentifrice or a conventional dentifrice, if toothbrushing occurs soon after meals.

J Dent Res 2005 84: 1133-1137. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Sealant and Fluoride Varnish in Caries: a Randomized Trial

M. Bravo, J. Montero, J.J. Bravo, P. Baca, and J.C. Llodra
Five years after discontinuation, the overall effect of a four-year varnish program remained significant.

J Dent Res 2005 84: 1138-1143. [Abstract] [Full Text] [Figures Only] [PDF]  

Effectiveness of 4 Pulpotomy Techniques—Randomized Controlled Trial

K.C. Huth, E. Paschos, N. Hajek-Al-Khatar, R. Hollweck, A. Crispin, R. Hickel, and M. Folwaczny
Calcium hydroxide is less appropriate for pulpotomies than is formocresol.

J Dent Res 2005 84: 1144-1148. [Abstract] [Full Text] [Figures Only] [PDF]  

Functional Gene Polymorphisms in Aggressive and Chronic Periodontitis

P.M. Brett, P. Zygogianni, G.S. Griffiths, M. Tomaz, M. Parkar, F. D’Aiuto, and M. Tonetti
There are shared and unique genetic associations in aggressive and chronic periodontitis.

J Dent Res 2005 84: 1149-1153. [Abstract] [Full Text] [PDF]  

Does Periodontal Treatment Improve Glycemic Control in Diabetic Patients? A Meta-analysis of Intervention Studies

S.-J. Janket, A. Wightman, A.E. Baird, T.E. Van Dyke, and J.A. Jones
The authors were unable to reject their null hypothesis that periodontal treatment does not affect glycemic control in patients with diabetes.

J Dent Res 2005 84: 1154-1159. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biomaterials & Bioengineering:

Hydrolytic Stability of Self-etch Adhesives Bonded to Dentin

S. Inoue, K. Koshiro, Y. Yoshida, J. De Munck, K. Nagakane, K. Suzuki, H. Sano, and B. Van Meerbeek
Long-term durability of adhesive-dentin bonds depends on the chemical bonding potential of the functional monomer.

J Dent Res 2005 84: 1160-1164. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Biological:

Streptococci Dominate the Diverse Flora within Buccal Cells

J.D. Rudney, R. Chen, and G. Zhang
This is the first study to show that the buccal mucosa have the potential to act as a reservoir for specific species currently recognized as periodontal pathogens.

J Dent Res 2005 84: 1165-1171. [Abstract] [Full Text] [Figures Only] [PDF]  

Control of Oral Biofilm Formation by an Antimicrobial Decapeptide

K.-P. Leung, T.D. Crowe, J.J. Abercrombie, C.M. Molina, C.J. Bradshaw, C.L. Jensen, Q. Luo, and G.A. Thompson
The synthetic decapeptide antimicrobial KSL may be a useful adjunct for conventional oral hygiene to prevent plaque-mediated dental diseases.

J Dent Res 2005 84: 1172-1177. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Role of TNF- and Its Receptors in Pericoronitis

A. Beklen, M. Laine, I. Ventä, T. Hyrkäs, and Y.T. Konttinen
In pericoronitis, inflammatory and resident cells produce and respond to potent pro-inflammatory cytokine TNF- with pathogenic and potential therapeutic relevance.

J Dent Res 2005 84: 1178-1182. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

2 Integrin +807 Polymorphism in Drug-induced Gingival Overgrowth

M. Ogino, J. Kido, M. Bando, N. Hayashi, C. Wada, T. Nagata, F. Nishimura, Y. Soga, S. Takashiba, T. Kubota, M. Itagaki, Y. Shimada, H. Tai, H. Yoshie, N. Yamazaki, Y. Shinohara, and M. Kataoka
This is the first study to demonstrate an association between 2 integrin polymorphism and drug-induced gingival overgrowth.

J Dent Res 2005 84: 1183-1186. [Abstract] [Full Text] [Figures Only] [PDF]  

Influence of Androgens on Gene Expression in the BALB/c Mouse Submandibular Gland

N.S. Treister, S.M. Richards, T. Suzuki, R.V. Jensen, and D.A. Sullivan
This is the first report of the magnitude of androgen influence on gene expression in submandibular tissue.

J Dent Res 2005 84: 1187-1192. [Abstract] [Full Text] [PDF] [Appendix]  

Clock Gene Expression in the Submandibular Glands

M. Furukawa, T. Kawamoto, M. Noshiro, K.K. Honda, M. Sakai, K. Fujimoto, S. Honma, K. Honma, T. Hamada, and Y. Kato
The Clock- and Cry-dependent molecular clock system is active in the salivary glands.

J Dent Res 2005 84: 1193-1197. [Abstract] [Full Text] [Figures Only] [PDF]  

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