D E P A R T M E N T S:

EDITORIAL:

Tooth Tissue Engineering and Regeneration—a Translational Vision!

Anthony J. (Tony) Smith
The Editor calls readers’ attention to two reports in this issue that highlight exciting advances in moving toward the tissue engineering of teeth.

J Dent Res 2004 83: 517. [Full Text] [PDF]  

RAPID COMMUNICATION:

Stem-cell-based Tissue Engineering of Murine Teeth

A. Ohazama, S.A.C. Modino, I. Miletich, and P.T. Sharpe
The authors present a significant advance toward the creation of artificial embryonic tooth primordia from cultured cells that can be used to replace missing teeth following transplantation into the adult mouth.

J Dent Res 2004 83: 518-522. [Abstract] [Full Text] [Figures Only] [PDF] Appendix  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Bioengineered Teeth from Cultured Rat Tooth Bud Cells

M.T. Duailibi, S.E. Duailibi, C.S. Young, J.D. Bartlett, J.P. Vacanti, and P.C. Yelick
Tooth-tissue-engineering methods can be used to generate both pig and rat tooth tissues.

J Dent Res 2004 83: 523-528. [Abstract] [Full Text] [Figures Only] [PDF]  

Enhanced Bone Apposition to a Chemically Modified SLA Titanium Surface

D. Buser, N. Broggini, M. Wieland, R.K. Schenk, A.J. Denzer, D.L. Cochran, B. Hoffmann, A. Lussi, and S.G. Steinemann
A modified sandblasted/acid-etched titanium surface promoted enhanced bone apposition during early stages of bone regeneration.

J Dent Res 2004 83: 529-533. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Streptococcus mutans Strains Harboring Collagen-binding Adhesin

Y. Sato, K. Okamoto, A. Kagami, Y. Yamamoto, T. Igarashi, and H. Kizaki
This is the first report demonstrating a collagen-binding adhesin from viridans streptococci in human oral indigenous flora.

J Dent Res 2004 83: 534-539. [Abstract] [Full Text] [Figures Only] [PDF]  

Monocyte Activation by Porphyromonas gingivalis LPS in Aggressive Periodontitis with the Use of Whole-blood Cultures

R. Mahanonda, N. Sa-Ard-Iam, O. Charatkulangkun, A. Promsudthi, R.E. Schifferle, K. Yongvanichit, and S. Pichyangkul
The authors did not observe hyper-responsiveness of monocytes to P. gingivalis LPS challenge in Thai patients with aggressive periodontitis.

J Dent Res 2004 83: 540-545. [Abstract] [Full Text] [Figures Only] [PDF]  

Identification of Genes Differentially Regulated in Rat Alveolar Bone Wound Healing by Subtractive Hybridization

T. Ohira, F. Myokai, N. Shiomi, K. Yamashiro, T. Yamamoto, Y. Murayama, H. Arai, F. Nishimura, and S. Takashiba
The differential expression of genes may be orchestrated with the inflammation, wound contraction, and formation of a connective tissue structure.

J Dent Res 2004 83: 546-551. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

vß3 Integrin Expression in Human Odontoblasts and Co-localization with Osteoadherin

M. Lucchini, M.-L. Couble, A. Romeas, M.-J. Staquet, F. Bleicher, H. Magloire, and J.-C. Farges
This is the first report of the presence of an integrin receptor, the vß3 integrin, in the cell membrane of human odontoblasts in vivo by in situ hybridization and immunochemistry.

J Dent Res 2004 83: 552-556. [Abstract] [Full Text] [Figures Only] [PDF]  

Characteristics of the Sarcoplasmic Reticulum Ca²⁺-dependent ATPase from Masticatory Muscles

G.A. Sánchez, D. Takara, A.F. Toma, and G.L. Alonso
The authors studied Ca-ATPase activity and calcium transport from sarcoplasmic reticulum membranes in masticatory muscles.

J Dent Res 2004 83: 557-561. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Do Circumstances in Early Life Contribute to Tooth Retention in Middle Age?

M.S. Pearce, J.G. Steele, J. Mason, A.W.G. Walls, and L. Parker
Results from a lifecourse study suggest that promotion of a healthier adult lifestyle and continued improvements in oral hygiene appear to be the public health interventions most likely to increase tooth retention in middle age.

J Dent Res 2004 83: 562-566. [Abstract] [Full Text] [Figures Only] [PDF]  

Salivary Agglutinin/DMBT1^SAG Expression is Up-regulated in the Presence of Salivary Gland Tumors

F.J. Bikker, J.E. van der Wal, A.J.M. Ligtenberg, J. Mollenhauer, J.M.A. de Blieck-Hogervorst, I. van der Waal, A. Poustka, and A.V. Nieuw Amerongen
In addition to its role in caries defense, salivary agglutinin may serve as a potential tumor indicator and/or tumor suppressor in salivary gland tissue.

J Dent Res 2004 83: 567-571. [Abstract] [Full Text] [Figures Only] [PDF]  

Cortical Neuromagnetic Fields Preceding Voluntary Jaw Movements

Y. Shibukawa, M. Shintani, T. Kumai, T. Suzuki, and Y. Nakamura
The primary motor cortex is involved in the programming of bilaterally symmetrical voluntary jaw movements as well as in their execution.

J Dent Res 2004 83: 572-577. [Abstract] [Full Text] [Figures Only] [PDF]  

Particle Size Distribution of Food Boluses after Mastication of Six Natural Foods

M.-A. Peyron, A. Mishellany, and A. Woda
The requirements that the food bolus must meet before it is ready to be swallowed are the same for everyone.

J Dent Res 2004 83: 578-582. [Abstract] [Full Text] [Figures Only] [PDF]  

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