D E P A R T M E N T S:

GUEST EDITORIAL:

Picture Talk—Effective Communication with Participants as a Critical Element in Oral Health Research

Beverly A. Dale, Patricia S. Brown, and Norma J. Wells
The authors describe an imaginative solution to communication issues affecting researchers and the communities they serve.

J Dent Res 2003 82: 669-670. [Full Text] [PDF]  

SPEECH:

Global Perspectives for the IADR and Dental Research

Stephen Challacombe
This is the text of the President-elect's address to the Opening Ceremonies of the 81st General Session of the International Association for Dental Research, June 25, 2003, Goteborg, Sweden.

J Dent Res 2003 82: 671. [Full Text] [PDF]  

DISCOVERY!:

Number Crunching with the Human Masticatory System

Jan Harm Koolstra
The author describes his involvement in unraveling the various aspects of masticatory function mechanics.

J Dent Res 2003 82: 672-676. [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Galanin-immunoreactive Nerve Fibers in the Periodontal Ligament during Experimental Tooth Movement

T. Deguchi, N. Takeshita, T.A. Balam, Y. Fujiyoshi, and T. Takano-Yamamoto
Galanin-containing nerve fibers in the periodontal ligament may play an important role in the response of the tissue to experimental tooth movement.

J Dent Res 2003 82: 677-681. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of Echistatin and an RGD Peptide on Orthodontic Tooth Movement

C. Dolce, A. Vakani, L. Archer, J.A. Morris-Wiman, and L.S. Holliday
This study shows the feasibility of using a non-biodegradable, sustained-release polymer to deliver integrin inhibitors adjacent to teeth to limit local tooth movement in response to orthodontic force.

J Dent Res 2003 82: 682-686. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of Matrix Metalloproteinase Inhibitors on Bone Resorption and Orthodontic Tooth Movement

L.S. Holliday, A. Vakani, L. Archer, and C. Dolce
Orthodontic tooth movement can be inhibited by MMP inhibitors, suggesting a mechanistic link between MMP activity and the production of RGD peptide.

J Dent Res 2003 82: 687-691. [Abstract] [Full Text] [Figures Only] [PDF]  

Behavior of SaOS-2 Cells Cultured on Different Titanium Surfaces

L. Postiglione, G. Di Domenico, L. Ramaglia, S. Montagnani, S. Salzano, F. Di Meglio, L. Sbordone, M. Vitale, and G. Rossi
Surface properties might be important for bone response around dental implants in vivo.

J Dent Res 2003 82: 692-696. [Abstract] [Full Text] [Figures Only] [PDF]  

Spectroscopic Imaging of Mineral Maturation in Bovine Dentin

K. Verdelis, M.A. Crenshaw, E.P. Paschalis, S. Doty, E. Atti, and A.L. Boskey
This study demonstrates the usefulness of both FTIR imaging and the fetal bovine tooth for characterizing changes in mineral properties of dentin during tooth development.

J Dent Res 2003 82: 697-702. [Abstract] [Full Text] [Figures Only] [PDF]  

Integrating Oxalate Desensitizers with Total-etch Two-step Adhesive

F.R. Tay, D.H. Pashley, Y.F. Mak, R.M. Carvalho, S.C.N. Lai, and B.I. Suh
The authors accepted their null hypothesis that the application of resin-free oxalate desensitizers to acid-etched dentin prior to adhesive application does not compromise the bonding of a total-etch adhesive to deep dentin.

J Dent Res 2003 82: 703-707. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Evidence of a Substantial Genetic Basis for IgG2 Levels in Families with Aggressive Periodontitis

S.R. Diehl, T. Wu, J.A. Burmeister, J.V. Califano, C.N. Brooks, J.G. Tew, and H.A. Schenkein
IgG2 host response genes may have minimal effects on localized disease.

J Dent Res 2003 82: 708-712. [Abstract] [Full Text] [Figures Only] [PDF]  

Oral Health Indicators Poorly Predict Coronary Heart Disease Deaths

R. Tuominen, A. Reunanen, M. Paunio, I. Paunio, and A. Aromaa
The associations between oral health indicators and coronary heart disease are mostly explained by confounding factors, particularly those relating to health behavior.

J Dent Res 2003 82: 713-718. [Abstract] [Full Text] [PDF]  

Alteration in Salivary Function in Early HIV Infection

A.L. Lin, D.A. Johnson, K.T. Stephan, and C.-K. Yeh
The authors suggest that salivary gland function is adversely affected early in HIV infection and that these changes do not appear to be compounded by the taking of xerostomic medications.

J Dent Res 2003 82: 719-724. [Abstract] [Full Text] [PDF]  

Biological:

Forward Mandibular Positioning Up-regulates SOX9 and Type II Collagen Expression in the Glenoid Fossa

A.B.M. Rabie, T.T. She, and V.R. Harley
Chondroid bone formation in the glenoid fossa in response to forward mandibular positioning is regulated by molecular markers indicative of endochondral ossification.

J Dent Res 2003 82: 725-730. [Abstract] [Full Text] [Figures Only] [PDF]  

A Repetitive, Steady Mouth Opening Induced an Osteoarthritis-like Lesion in the Rabbit Temporomandibular Joint

T. Fujisawa, T. Kuboki, T. Kasai, W. Sonoyama, S. Kojima, J. Uehara, C. Komori, H. Yatani, T. Hattori, and M. Takigawa
This is the first report elucidating the mechanism for generation of the sclerotic change in the subchondral bone of the TMJ.

J Dent Res 2003 82: 731-735. [Abstract] [Full Text] [Figures Only] [PDF]  

Multiple Dendritic Cell (DC) Subpopulations in Human Gingiva and Association of Mature DCs with CD4+ T-cells in situ

R. Jotwani and C.W. Cutler
This is the first demonstration of the presence of an additional subset of immature dendritic cells, besides Langerhans cells, in the inflamed gingiva.

J Dent Res 2003 82: 736-741. [Abstract] [Full Text] [Figures Only] [PDF]  

Human Dental Pulp Vasculogenesis Evaluated by CD34 Antigen Expression and Morphological Arrangement

O. Trubiani, D. Tripodi, T. Delle Fratte, S. Caputi, and R. Di Primio
The process of vasculogenesis persists into adult life, where it contributes to continuous adjustment of vessel and network structures in response to functional needs and dental tissue homeostasis.

J Dent Res 2003 82: 742-747. [Abstract] [Full Text] [Figures Only] [PDF]  

Calcium Blocks Fungicidal Activity of Human Salivary Histatin 5 through Disruption of Binding with Candida albicans

J. Dong, S. Vylkova, X.S. Li, and M. Edgerton
Calcium is a potent inhibitor of salivary histatin 5 candidacidal activity at physiological concentrations and may be the primary salivary ion responsible for the masking effect of saliva.

J Dent Res 2003 82: 748-752. [Abstract] [Full Text] [Figures Only] [PDF]  

Degradation of Antimicrobial Histatin-variant Peptides in Staphylococcus aureus and Streptococcus mutans

J. Groenink, A.L.A. Ruissen, D. Lowies, W. van ’t Hof, E.C.I. Veerman, and A.V. Nieuw Amerongen
The authors investigated whether different bacteria possess proteolytic activity that may function as a protective mechanism by affecting the antimicrobial activity of histatin 5 and its variant peptides.

J Dent Res 2003 82: 753-757. [Abstract] [Full Text] [Figures Only] [PDF]  

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