D E P A R T M E N T S:

GUEST EDITORIAL:

It’s Never All Black and White

Michael L. Barnett
J Dent Res 2003 82: 580. [Full Text] [PDF]  

ADA RESEARCH AGENDA:

2003 ADA RESEARCH AGENDA

J Dent Res 2003 82: 661-663. [Full Text] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Bone with a Vascular Flap Induced from Fat Tissue with the Use of rhBMP-2 in Rats

M. Hosoya, Y. Maruoka, M. Oda, I. Asahina, S. Ichinose, and K. Omura
This is the first report on bone induction from fat tissue by recombinant human bone morphogenetic protein in vivo.

J Dent Res 2003 82: 581-584. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of Implant Healing Time on Crestal Bone Loss of a Controlled-load Dental Implant

C.C. Ko, W.H. Douglas, R. DeLong, M.D. Rohrer, J.Q. Swift, J.S. Hodges, K.-N. An, and E.L. Ritman
Loading and bioactivities of osteoblasts exert a synergistic effect on osseointegration that is likely to support the hypothesis that early loading produces more favorable osseointegration.

J Dent Res 2003 82: 585-591. [Abstract] [Full Text] [Figures Only] [PDF]  

Adhesive Resin Induces Apoptosis and Cell-cycle Arrest of Pulp Cells

M.G. Mantellini, T.M. Botero, P. Yaman, J.B. Dennison, C.T. Hanks, and J.E. Nör
An adhesive resin induces apoptosis and cell-cycle arrest of cells involved in the regeneration of the dentin-pulp complex in vitro.

J Dent Res 2003 82: 592-596. [Abstract] [Full Text] [Figures Only] [PDF]  

Effects of HEMA/Solvent Combinations on Bond Strength to Dentin

R.M. Carvalho, J.S. Mendonça, S.L. Santiago, R.R. Silveira, F.C.P. Garcia, F.R. Tay, and D.H. Pashley
The solubility parameters of HEMA/solvent mixtures can significantly alter bond strengths to dentin, by modifying the final degree of expansion of dried matrix.

J Dent Res 2003 82: 597-601. [Abstract] [Full Text] [Figures Only] [PDF]  

Artifacts from Dental Casting Alloys in Magnetic Resonance Imaging

F. Shafiei, E. Honda, H. Takahashi, and T. Sasaki
Titanium alloys pose a problem with respect to causing magnetic resonance imaging artifacts.

J Dent Res 2003 82: 602-606. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Expression of an Inhibitor of Apoptosis, Survivin, in Oral Carcinogenesis

C. Tanaka, K. Uzawa, T. Shibahara, H. Yokoe, H. Noma, and H. Tanzawa
Survivin plays an important role during oral carcinogenesis, and gene expression may be regulated by an epigenetic mechanism.

J Dent Res 2003 82: 607-611. [Abstract] [Full Text] [Figures Only] [PDF]  

Single-nucleotide Polymorphism in the CD14 Promoter and Periodontal Disease Expression in a Japanese Population

K. Yamazaki, K. Ueki-Maruyama, T. Oda, K. Tabeta, Y. Shimada, H. Tai, T. Nakajima, H. Yoshie, D. Herawati, and G.J. Seymour
In subjects with periodontitis, expression of single-nucleotide polymorphism may be related to early disease activity.

J Dent Res 2003 82: 612-616. [Abstract] [Full Text] [Figures Only] [PDF]  

Task-dependence of Jaw Elevator and Depressor Co-activation

P.A. Proeschel and J. Raum
Depressor counteraction has only a minor influence on the generation of surplus muscle activity in chewing.

J Dent Res 2003 82: 617-620. [Abstract] [Full Text] [Figures Only] [PDF]  

Biological:

Differential Injury Responses in Oral Mucosal and Cutaneous Wounds

A.M. Szpaderska, J.D. Zuckerman, and L.A. DiPietro
Diminished inflammation is a key feature in the privileged repair of oral mucosa.

J Dent Res 2003 82: 621-626. [Abstract] [Full Text] [Figures Only] [PDF]  

PTHrP Regulates Chondrocyte Maturation in Condylar Cartilage

A.B.M. Rabie, G.H. Tang, H. Xiong, and U. Hägg
Mandibular advancement promotes mesenchymal cell differentiation and triggers PTHrP expression, which retards further maturation to allow for more growth.

J Dent Res 2003 82: 627-631. [Abstract] [Full Text] [Figures Only] [PDF]  

Accelerated Alveolar Bone Loss in Mice Lacking Interleukin-10

A. Al-Rasheed, H. Scheerens, D.M. Rennick, H.M. Fletcher, and D.N. Tatakis
Lack of interleukin-10 leads to accelerated alveolar bone loss.

J Dent Res 2003 82: 632-635. [Abstract] [Full Text] [Figures Only] [PDF]  

Novel OK-432-conjugated Tumor Vaccines Induce Tumor-specific Immunity against Murine Tongue Cancer

X. Li, H. Bukawa, M. Hirota, Y. Tsuyuki, S. Omura, and K. Fujita
The authors describe a new tumor vaccine method that may be a strong candidate for clinical use.

J Dent Res 2003 82: 636-640. [Abstract] [Full Text] [Figures Only] [PDF]  

Gene Profiling in Human Periodontal Ligament Fibroblasts by Subtractive Hybridization

T. Yamamoto, F. Myokai, F. Nishimura, T. Ohira, N. Shiomi, K. Yamashiro, H. Arai, Y. Murayama, and S. Takashiba
Human periodontal ligament fibroblasts express many previously unreported genes associated with maturation and differentiation, but expression can differ in vitro and in vivo.

J Dent Res 2003 82: 641-645. [Abstract] [Full Text] [Figures Only] [PDF]  

Expression of MMP-8 and MMP-13 Genes in the Periodontal Ligament during Tooth Movement in Rats

I. Takahashi, M. Nishimura, K. Onodera, J.-W. Bae, H. Mitani, M. Okazaki, Y. Sasano, and H. Mitani
Expression of MMP-8 and MMP-13 is differentially regulated by tension and compression and plays an important role in the remodeling of the periodontal ligament.

J Dent Res 2003 82: 646-651. [Abstract] [Full Text] [Figures Only] [PDF]  

TGF-ß1 Induces Accumulation of Dendritic Cells in the Odontoblast Layer

J.-C. Farges, A. Romeas, M. Melin, J.-J. Pin, S. Lebecque, M. Lucchini, F. Bleicher, and H. Magloire
TGF-ß1 released from dentin degraded by bacterial or iatrogenic agents could be involved in the immune response of the dental pulp resulting from tooth injury.

J Dent Res 2003 82: 652-656. [Abstract] [Full Text] [Figures Only] [PDF]  

Age-related Changes in Brain Regional Activity during Chewing: A Functional Magnetic Resonance Imaging Study

M. Onozuka, M. Fujita, K. Watanabe, Y. Hirano, M. Niwa, K. Nishiyama, and S. Saito
Chewing causes regional increases in neuronal activity in the brain, some of which are age-related.

J Dent Res 2003 82: 657-660. [Abstract] [Full Text] [Figures Only] [PDF]  

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