D E P A R T M E N T S:

GUEST EDITORIAL:

Smallpox: The Main Site of Transmission is the Oropharynx

Samuel Baron
The author believes that resumption of studies of oropharyngeal shedding of poxviruses and methods for interruption should be given high priority by scientists in the dental and infectious disease areas of research.

J Dent Res 2003 82: 252. [Full Text] [PDF]  

DISCOVERY!:

Dental Caries Seen from the Pulpal Side: a Non-traditional Approach

M. Larmas
The author challenges oral biologists to join the research family interested in dental caries, to broaden the approach from pure chemistry to applied biology of dentin.

J Dent Res 2003 82: 253-256. [Full Text] [PDF]  

ERRATUM:

ERRATUM

J Dent Res 2003 82: 326. [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biomaterials & Bioengineering:

Dissociation States of Collagen Functional Groups and their Effects on the Priming Efficacy of HEMA Bonded to Collagen

N. Nishiyama, K. Suzuki, A. Nagatsuka, I. Yokota, and K. Nemoto
Inhibiting the dissociation of the carboxylic acid or the amine of a collagen functional group resulted in enhanced bonding of resin to collagen fiber.

J Dent Res 2003 82: 257-261. [Abstract] [Full Text] [Figures Only] [PDF]  

Shear in Flexure of Fiber Composites with Different End Supports

K.A. Eckrote, C.J. Burstone, M.A. Freilich, G.E. Messer, and A.J. Goldberg
This study determined whether the flexure behavior of uniform fiber-reinforced composite beams with restrained or simply supported ends and various length/depth aspect ratios could be more accurately modeled by correcting for shear.

J Dent Res 2003 82: 262-266. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

Effects of Fluoride and Aluminum from Ionomeric Materials on S. mutans Biofilm

M.F. Hayacibara, O.P.S. Rosa, H. Koo, S.A. Torres, B. Costa, and J.A. Cury
Aluminum released by ionomeric materials may enhance the biological effects of fluoride.

J Dent Res 2003 82: 267-271. [Abstract] [Full Text] [Figures Only] [PDF]  

Clinical:

Correlations of the Expression of Fibroblast Growth Factor-2, Vascular Endothelial Growth Factor, and their Receptors with Angiogenesis in Synovial Tissues from Patients with Internal Derangement of the Temporomandibular Joint

J. Sato, N. Segami, Y. Yoshitake, and K. Nishikawa
This is the first report on the expression of fibroblast growth factors in the synovial tissues of patients with internal derangement of the TMJ.

J Dent Res 2003 82: 272-277. [Abstract] [Full Text] [Figures Only] [PDF]  

Hemispheric Dominance of Tongue Control Depends on the Chewing-side Preference

H. Shinagawa, T. Ono, Y. Ishiwata, E. Honda, T. Sasaki, M. Taira, A. Iriki, and T. Kuroda
This is the first study to demonstrate clearly that the S1/M1 contralateral to chewing-side preference is dominant in tongue motor function, indicating that the masticatory system concurrently maximizes jaw and tongue function.

J Dent Res 2003 82: 278-283. [Abstract] [Full Text] [Figures Only] [PDF]  

Evidence that Experimentally Induced Sleep Bruxism is a Consequence of Transient Arousal

T. Kato, J.Y. Montplaisir, F. Guitard, B.J. Sessle, J.P. Lund, and G.J. Lavigne
Sleep bruxism is an exaggerated form of oromotor activity associated with sleep micro-arousal.

J Dent Res 2003 82: 284-288. [Abstract] [Full Text] [Figures Only] [PDF]  

MSX1 and TGFB3 Contribute to Clefting in South America

A.R. Vieira, I.M. Orioli, E.E. Castilla, M.E. Cooper, M.L. Marazita, and J.C. Murray
The authors suggest that MSX1 and TGFB3 mutations make a contribution to clefts in South American populations.

J Dent Res 2003 82: 289-292. [Abstract] [Full Text] [PDF]  

Biological:

Bone Formation by BMP-7-transduced Human Gingival Keratinocytes

R.B. Rutherford, P. Racenis, S. Fatherazi, and K. Izutsu
BMP-transduced human oral keratinocyte cells secrete BMP and form bone in vivo but, unlike BMP-transduced human gingival fibroblasts, do not transdifferentiate to osteoblasts.

J Dent Res 2003 82: 293-297. [Abstract] [Full Text] [Figures Only] [PDF]  

Regulation of Osteoprotegerin Gene Expression in Dental Follicle Cells

G.E. Wise, Y. Ren, and S. Yao
The down-regulation of osteoprotegerin allows osteoclast formation to occur, and either colony-stimulating factor 1 or parathyroid-hormone-related protein may cause this by down-regulating the gene expression of protein kinase C-a.

J Dent Res 2003 82: 298-302. [Abstract] [Full Text] [Figures Only] [PDF]  

Differences Between Tooth Stimulation and Capsaicin-induced Neurogenic Vasodilatation in Human Gingiva

P. Kemppainen, N.-L. Avellan, H.O. Handwerker, and C. Forster
This is the first time that laser Doppler imaging has been applied to record blood flow in human gingiva.

J Dent Res 2003 82: 303-307. [Abstract] [Full Text] [Figures Only] [PDF]  

ß₂-Adrenoceptor Regulation of CGRP Release from Capsaicin-sensitive Neurons

W.R. Bowles, C.M. Flores, D.L. Jackson, and K.M. Hargreaves
This is the first study supporting the hypothesis that, since capsaicin selectively activates nociceptors, ß2-adrenoceptor agonists may have clinical utility as peripherally acting therapeutics for dental pain and inflammation.

J Dent Res 2003 82: 308-311. [Abstract] [Full Text] [Figures Only] [PDF]  

Patterns of Fluoro-Gold Entry into Rat Molar Enamel, Dentin, and Pulp

M.R. Byers and K.J. Yoon Lin
This is the first demonstration of trans-dental passage and long-term odontoblastic retention of an orally applied label in intact vital teeth.

J Dent Res 2003 82: 312-317. [Abstract] [Full Text] [Figures Only] [PDF] [Appendix]  

New Animal Model for Studying Mastication in Oral Motor Disorders

I. Okayasu, Y. Yamada, S. Kohno, and N. Yoshida
Mice are appropriate models for the study of mastication.

J Dent Res 2003 82: 318-321. [Abstract] [Full Text] [Figures Only] [PDF]  

The Effect of High Sugar Intake on the Development of Periradicular Lesions in Rats with Type 2 Diabetes

A. Iwama, N. Nishigaki, K. Nakamura, I. Imaizumi, N. Shibata, M. Yamasaki, H. Nakamura, Y. Kameyama, and Y. Kapila
The metabolic conditions produced by type 2 diabetes enhance the development of periradicular lesions in rats.

J Dent Res 2003 82: 322-325. [Abstract] [Full Text] [Figures Only] [PDF]  

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