D E P A R T M E N T S:

LETTER TO THE EDITOR:

TO THE EDITOR:

Ivar A. Mjör
J Dent Res 2002 81: 372. [Full Text] [PDF]  

TO THE EDITOR: • THE AUTHORS REPLY

Mike Rethman, Philippe P. Hujoel, Mark T. Drangsholt, Charles F. Spiekerman, and Timothy A. DeRouen
J Dent Res 2002 81: 372-374. [Full Text] [PDF]  

GUEST EDITORIAL:

The Need for the IADR to Sponsor a Voluntary Review of Protocols–Before the Research has Begun

Steven M. Pollock
J Dent Res 2002 81: 375. [Full Text] [PDF]  

RAPID COMMUNICATION:

Attenuation of Glucan-binding Protein C Reduces the Cariogenicity of Streptococcus mutans: Analysis of Strains Isolated from Human Blood

K. Nakano, M. Matsumura, M. Kawaguchi, T. Fujiwara, S. Sobue, I. Nakagawa, S. Hamada, and T. Ooshima
A variation in glucan-binding protein C may cause a weak immune response, allowing S. mutans to survive in the bloodstream.

J Dent Res 2002 81: 376-379. [Abstract] [Full Text] [Figures Only] [PDF]  

R E S E A R C H  R E P O R T S:

Biological:

Inactivation of the Streptococcus mutans fxpC Gene Confers Resistance to Xylitol, a Caries-preventive Natural Carbohydrate Sweetener

H. Benchabane, L.-A. Lortie, N.D. Buckley, L. Trahan, and M. Frenette
Inactivation of the fxpC gene confers resistance to xylitol, confirming its function.

J Dent Res 2002 81: 380-386. [Abstract] [Full Text] [Figures Only] [PDF]  

Noggin Blocks Osteoinductive Activity of Porcine Enamel Extracts

T. Iwata, Y. Morotome, T. Tanabe, M. Fukae, I. Ishikawa, and S. Oida
This is the first study to show that porcine enamel extracts contain bone morphogenetic proteins that contribute to the induction of biomineralization.

J Dent Res 2002 81: 387-391. [Abstract] [Full Text] [Figures Only] [PDF]  

The Expression of Dentin Sialophosphoprotein Gene in Bone

C. Qin, J.C. Brunn, E. Cadena, A. Ridall, H. Tsujigiwa, H. Nagatsuka, N. Nagai, and W.T. Butler
Dentin sialophosphoprotein (DSPP) is not tooth-specific, and dramatically different regulatory mechanisms governing DSPP expression are involved in the bone and dentin.

J Dent Res 2002 81: 392-394. [Abstract] [Full Text] [Figures Only] [PDF]  

Interferon-gamma Deficiency Attenuates Local P. gingivalis-induced Inflammation

Y. Houri-Haddad, W.A. Soskolne, E. Shai, A. Palmon, and L. Shapira
Suppression of IFN{gamma} levels may be sufficient to control the levels of TNF-{alpha} and IL-1ß at the inflammatory site, suggesting another possible therapeutic modality for inhibiting bone loss.

J Dent Res 2002 81: 395-398. [Abstract] [Full Text] [Figures Only] [PDF]  

Identification of Genes Differentially Expressed in Cultured Human Periodontal Ligament Fibroblasts vs. Human Gingival Fibroblasts by DNA Microarray Analysis

X. Han and S. Amar
Periodontal ligament fibroblasts and gingival fibroblasts appear to display different gene expression patterns that may reflect intrinsic functional differences of the two cell populations and may well coordinate with their tissue-specific activities.

J Dent Res 2002 81: 399-405. [Abstract] [Full Text] [Figures Only] [PDF]  

Estrous-cycle-dependent Variation in Orthodontic Tooth Movement

N. Haruyama, K. Igarashi, S. Saeki, M. Otsuka-Isoya, H. Shinoda, and H. Mitani
Cyclic changes in the estradiol level may be associated with the estrous-cycle-dependent variation in tooth movement through its effects on bone resorption.

J Dent Res 2002 81: 406-410. [Abstract] [Full Text] [Figures Only] [PDF]  

Roles of Salivary Proteins in the Adherence of Oral Streptococci to Various Orthodontic Brackets

S.-J. Ahn, H.-S. Kho, S.-W. Lee, and D.-S. Nahm
Salivary pellicles were found to play a significant role in the initial adhesion of oral streptococci to orthodontic brackets.

J Dent Res 2002 81: 411-415. [Abstract] [Full Text] [Figures Only] [PDF] [Electronic Appendix]  

Clinical:

Salivary Defense Factors in Herpes Simplex Virus Infection

H. Välimaa, M. Waris, V. Hukkanen, M.F.J. Blankenvoorde, A.V. Nieuw Amerongen, and J. Tenovuo
Saliva contains factors, in addition to anti-herpes simplex virus (HSV) immunoglobulins, that neutralize HSV and may indirectly contribute to the control of recurrent labial herpes.

J Dent Res 2002 81: 416-421. [Abstract] [Full Text] [Figures Only] [PDF]  

¹H and ¹³C NMR Spectroscopic Analysis of Human Saliva

C.J.L. Silwood, E. Lynch, A.W.D. Claxson, and M.C. Grootveld
This is the first report of the applications of two-dimensional NMR techniques to the multicomponent analysis of human saliva.

J Dent Res 2002 81: 422-427. [Abstract] [Full Text] [Figures Only] [PDF] [Electronic Appendix]  

Volume Changes in Human Masticatory Muscles between Jaw Closing and Opening

T.K. Goto, K. Tokumori, Y. Nakamura, M. Yahagi, K. Yuasa, K. Okamura, and S. Kanda
This is the first report to quantify the volume changes of the masseter, medial, and lateral pterygoid muscles during jaw opening.

J Dent Res 2002 81: 428-432. [Abstract] [Full Text] [Figures Only] [PDF]  

Biomaterials & Bioengineering:

Materials Design of Ceramic-based Layer Structures for Crowns

B.R. Lawn, Y. Deng, I.K. Lloyd, M.N. Janal, E.D. Rekow, and V.P. Thompson
This study provides simple a priori predictions of failure in prospective ceramic/ substrate bilayers and ranks ceramic materials for best clinical performance.

J Dent Res 2002 81: 433-438. [Abstract] [Full Text] [Figures Only] [PDF]  

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