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Figure 1. Pg LPS stimulated IL-18 and IL-18BPa production by THP1 monocytes. (A) Pg and E. coli LPS (100 ng/mL) increased IL-18 production in THP1 monocytes after 6–24 hrs. (B) Pg and E. coli LPS (100 ng/mL) increased IL-18BPa production in THP1 monocytes after 6–24 hrs. IL-18 and IL-18BPa levels were measured by ELISA and compared with unstimulated cells (controls). Each value is a mean (± SD) of 3 experiments recorded on 3 separate occasions. *p < 0.05 compared with controls.