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Figure 1. Alveolar bone loss and SFRP1 expression in the P. gingivalis-induced murine periodontitis model. (A) Morphometric images for alveolar bone loss on day 10 in the control and the infected animals. (B–D) Quantification of SFRP1-immunopositive cells identified by immunohistochemical staining: (B) inflammatory cells, (C) fibroblasts, and (D) bone-lining cells. Data represent mean values ± SEM (N = 6 for the control group, N = 5 for the infected group at each time-point). *Statistically significant at p < 0.05 by Student’s t test.
