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Figure 3. Effect of cyclo-oxygenase-2 inhibitor on arousals in the acute inflammatory model induced by Freunds adjuvant application in the TMJ on 2 light periods of recording. SHAM group: injected with saline. FA group: injected with Freunds adjuvant. Saline (SHAM/COX2i) and Freunds adjuvant (FA/COX2i) injected into the TMJ treated with etoricoxib (COX-2i, 90 mg/kg, p.o.). The values are expressed as mean ± SD. *Differ from SHAM group (p < 0.05). #Differ from Freunds adjuvant group (p < 0.05). N = 8/group.