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Figure 2. Effect of cyclo-oxygenase-2 inhibitor on sleep latency (A) and REM sleep latency (B) in the acute inflammatory model induced by Freund’s adjuvant application in the TMJ on 2 light periods of recording. SHAM group: injected with saline. FA group: injected with Freund’s adjuvant. Saline (SHAM/COX2i) and Freund’s adjuvant (FA/COX2i) injected into the TMJ treated with etoricoxib (COX-2i, 90 mg/kg, p.o.). The values are expressed as mean ± SD. *Differ from the SHAM group (p < 0.001). 
Differ from first day of SHAM/COX2i group (p < 0.01). 
Differ from first day of the FA/COX2i group (p < 0.05). N = 8/group.
