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Figure 3. P. gingivalis-specific IgG subclass responses against sonicates of P. gingivalis. Immunization groups of BALB/c mice immunized with rgpA DNA vaccine via abdominal skin by Gene Gun (2.5 µg/mouse) or immunized nasally with rgpA-HVJ envelope vector (20 µg/mouse). IgG subclass responses were assessed on day 49. Results are means ± standard deviations of log2 ELISA antibody titers (N = 15). Variation in endpoint titers was within a two-fold serial dilution. One-way ANOVA for repeated measurements was used for inter-group comparisons. The Student-Newman-Keuls test was used for multiple comparisons.
