Click on image to view larger version.
Figure 2. The frequency of cytokine-secreting cells in the oral mucosa and the submandibular salivary glands of normal rhesus macaques. (A) The frequency of cytokine-secreting cells in the buccal mucosa of normal macaques. (B) The frequency of cytokine-secreting cells in the submandibular salivary glands of normal monkeys. The bars represent the mean ± standard error. The numbers of TNF-
-secreting cells were predominant over other types of cytokine-secreting cells examined. The buccal mucosa contained a high frequency of TNF--, IL-10-, IL-6-, and IFN-
-secreting cells, which were about 10 times as high as that of submandibular glands. Results were obtained from fresh mononuclear cells isolated from the cheek mucosa and submandibular glands of 5 normal rhesus macaques.
