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Figure 2. C. rectus infection induced structural abnormalities in the placenta. H&E staining from unchallenged (a,b) and growth-restricted challenged (c,d) placentas. In the intra-uterine growth-restricted challenged samples (n = 12), there is a significant relative decrease in the labyrinth area, with a concomitant increase in the decidua when compared with the control samples (n = 8). The spongiotrophoblast layer (S) is not altered. (e) Statistical analysis was performed with one-way ANOVA. *p < 0.001, **p = 0.04. (b,d) Histological sections indicated by rectangles in (a) and (c) with high-power magnification. Scale bar in (a) and (c), 500 µm, and in (b) and (d), 125 µm. (L) labyrinth, (S) spongiotrophoblast layer, (Sp) spongiotrophoblast cells, (D) decidua.
