Click on image to view larger version.
Figure 2. Comparison between Sham and ovariectomized groups. (A) Serum estradiol concentrations at different time-points. Values are presented as means ± standard deviations (SDs) of 6 monkeys in each group. aSignificantly different from the baseline value of the same operational group (P < 0.05). bSignificantly different from the Sham value (P < 0.05). (B) Body weight at different time-points. Values are presented as means ± standard deviations (SDs) of 6 monkeys in each group. No significant differences were found between groups. (C) Changes in lumbar bone mineral density. aSignificantly different from the baseline bone mineral density of the same operational group (P < 0.05). bSignificantly different from the Sham value at the same time-point (P < 0.05). (D) % of baseline lumbar bone mineral densities which were calculated by the following equation: ({Final lumbar bone mineral density /baseline lumbar bone mineral density} X 100). The coefficient of variation of dual-energy x-ray absorptiometry measurement was less than 2%. bSignificantly different from the Sham value (P < 0.05). (E) Results of 3D morphometric analysis of the alveolar bone. Values are presented as means ± SDs of 6 monkeys in each group. No significant differences were found between groups. (F) Results of node-strut analysis of the alveolar bone. Values are presented as means ± SDs of 6 monkeys in each group. bSignificantly different from the Sham value (P < 0.05). (G) Results of trabecular architectural morphometry of the alveolar bone. Values are presented as means ± SDs of 6 monkeys in each group. bSignificantly different from the Sham value (P < 0.05). (H) Number of pores in the different walls of the alveolar socket. Significant difference was found between the Sham and the ovariectomized groups at the top of the interradicular septum. Values are presented as means ± SDs of 6 monkeys in each group. bSignificantly different from the Sham value (P < 0.05). (I) Loss of buccal alveolar crest height. Values are presented as means ± SDs of 6 monkeys in each group. No significant differences were found between groups. (J) Attrition degree according to Amano’s classification. Values are presented as means ± SDs of 6 monkeys in each group. No significant differences were found between groups.
