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Figure 3. Brd U incorporation into amelogenin-treated dental pulp cells. (A) Proliferation as measured by BrdU incorporation was increased in the presence of rH58 at concentrations from 50 to 200 ng/mL, with 200 ng/mL as the optimal concentration. (B) rH72 enhanced dental pulp cell proliferation at concentrations from 20 to 1000 ng/mL, with 200 ng/mL as optimal. (C) Cell-cycle superarray results showed that CKD6, CUL4, and NEDD8 were up-regulated more than 2 times by rH58 by dental pulp cells. Results represent the means ± SE. Asterisks show significant differences. *P < 0.05 vs. control. N (for each cell of data) = 3.
