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Figure 2. Effect of clodronate on gene expression for cyclo-oxygenase-2 (COX-2) and receptor activator nuclear factor 
B ligand (RANKL) in compressed periodontal ligament cells. (A) RT-PCR for COX-2, RANKL, and ß-actin. CLO: 125 µM. (B) Relative expression of RANKL mRNA and COX-2 mRNA determined by densitometric analysis. Values were corrected for ß-actin mRNA expression. Representative results of 1 of 3 independent experiments are shown. CLO: clodronate (5, 25, 125 µM).
