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Figure 2. Effects of different magnitudes of compressive force on sRANKL (A) and OPG (B) production by human PDL cells. Human PDL cells were cultured with or without the indicated magnitudes of compressive force for 12 hrs. Data are expressed as the mean ± SD of 5 independent cultures. The cytokines were changed by application of compressive force in a force-magnitude-dependent manner (p < 0.001, by two-way ANOVA). Significantly different from the corresponding control: *p < 0.001. Significantly different from non-resorption (with compressive force) at each magnitude: #p < 0.001.