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Figure 1. Effects of incubation time with compressive force on sRANKL (A) and OPG (B) production in conditioned media of human PDL cells. Production of these cytokines was assayed as described in MATERIALS & METHODS. Data are expressed as the mean ± SD of 5 independent cultures. Cytokine production was changed by application of compressive force (2.0 g/cm2), and the pattern was time-dependent (p < 0.001, by two-way ANOVA). Significantly different from the corresponding control at each incubation time: *p < 0.001. Significantly different from non-resorption (with compressive force) at each incubation time: #p < 0.001.
