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Figure 1. Plots depicting RANKL (A, pg/mg protein) and OPG (B, pg/mg protein) concentrations, and the RANKL:OPG ratio (C) in the synovial fluid of joints with disk displacement with reduction (DDwR), joints with disk displacement without reduction (DDw/oR), and osteoarthritis (OA) in patients and control participants. The content of RANKL in the synovial fluid was determined by an ELISA, and that of OPG, by a commercially available ELISA. Data are expressed as the mean ± SEM. Data from control (Cont; n = 13), DDwR (n = 25), DDw/oR (n = 39), and osteoarthritis (OA; n = 53) participants were analyzed. Fisher’s protected least-significant-difference post hoc test was used when multiple groups were compared with a single control group. **P < 0.01, ***P < 0.005 (compared with the control), and #P < 0.05, ##P < 0.01, and ###P < 0.005, as indicated by the brackets.
