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Figure 2. Effect of treating macrophages with fraction 1 (non-dialyzable material of cranberry juice), fraction 2 (cranberry juice), and epigallocatechin gallate (EGCG) on the secretion of IL-8 (A) and RANTES (B) induced by LPS (1 µg/mL) of A. actinomycetemcomitans ATCC 29522 for 24 hrs. Macrophages were treated with cranberry fractions, or EGCG, for 2 hrs before lipopolysaccharides (LPS) stimulation. Cytokine secretion was assessed by ELISA. The data are the means ± standard deviations of triplicate assays for three independent experiments. *P value of < 0.05 compared with untreated control.
