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Figure 4. Effect of TGF-ß on signal transduction of BMP. C2C12 cells were transfected with Id1 gene, then treated with (A) 100 ng/mL BMP2 and 10 ng/mL TGF-ß1, and with (B) BMP-like fraction (fractions 4-6) in Emd-Gel added to TGF-ß and TGF-ß-like fraction (fractions 8-13) in Emd-Gel. Luciferase activity was measured after an overnight incubation. Data are means ± SE of 4 culture wells. *p < 0.05, **p < 0.001.

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