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Figure. The myofibroblast differentiation model. {Uparrow} indicates a stimulation of differentiation and {Downarrow} an inhibition of differentiation. Abbreviations: F = fibroblast; Proto-MF = proto-myofibroblast; mature MF = mature myofibroblast; PDGF = platelet-derived growth factor; TGF-ß = transforming growth factor ß; ED-A FN = ED-A (EIIIA) variant of fibronectin; GM-CSF = granulocyte/macrophage-colony-stimulating factor; IFN-{gamma} = interferon-{gamma}; bFGF = basic fibroblast growth factor; PGE2 = prostaglandin E2.





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IADR Journals Advances in Dental Research ®
Journal of Dental Research ® Critical Reviews (1990-2004)