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Figure 2. Pathological evaluation. (a,b) Control group at week 4. (c,d) 20 mg/kg/day group at week 4. (e,f) Control group at week 8. (g,h) 20 mg/kg/day group at week 8. Panels b, d, f, and h are high-magnification views of the periapical lesions shown in panels a, c, e, and g, respectively. AA, Apical Abscess; CE, Cementum; B, Bone. Scale bars: a, c, e, g = 250 µm; b, d, f, h = 50 µm.

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