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Figure 2. Means plots ± 95% confidence intervals of enamel mineral (ash) weight (A), protein content (B), mineral-to-protein (M:P) ratios (C), and percent mineral by weight (D) for wild-type (circles) vs. MMP-20 null (squares) incisors as a function of developmental stage (S, secretory; EM, early mature; NM, nearly mature). Differences in mineral content magnify as enamel development proceeds (A, S
NM), and more protein appears to be retained in the nearly mature enamel of the MMP-20 null mice (B, NM). Ratio (C) and percent mineral by weight (D) differences are significant only relative to nearly mature enamel (NM; see also Table), when MMP-20 is not normally expressed (N values are provided in the Table).