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Figure 4. Biological effects of chondroitin-4-sulfate. (A) Palatal fibroblasts cultured for 8 hrs in medium supplemented with chondroitin-4-sulfate showed a dose-dependent reduction in cell adhesion (one-way ANOVA; p = 0.0049). (B) In the cell proliferation assay, statistical comparison shows that continuous supplementation of the culture medium with chondroitin-4-sulfate led to a dose-dependent increase in cell numbers after a seven-day culture period (p = 0.0074). Values represent mean ± SEM of 3 experiments.
