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Figure 3. Synthesis of extracellular matrix (ECM) proteins and integrin expression in SaOS-2 cells on titanium surfaces. (A) ECM protein synthesis (mean ± SD, n = 12) determined by enzyme-linked immunoassay in situ at different time points: (a) collagen I (CoI), (b) fibronectin (FN), (c) vitronectin (VN), and (d) tenascin (TN). (B) Integrin expression (mean ± SD, n = 12) determined by flow cytometric analysis at 96 hrs of culture. *p < 0.05, titanium plasma-sprayed (TPS) vs. sandblasted (SB) and smooth (S) surfaces.
