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Figure 2. State of survivin protein expression in normal tissues (n = 71), leukoplakias (n = 38), and primary OSCCs (n = 71). The survivin-IHC scores were calculated as follows: survivin-IHC score = (the percentage of positive tumor cells) X the staining intensity. Survivin protein expressions in leukoplakias and OSCCs were significantly higher than in normal oral tissues (p < 0.0001, Student’s t test), whereas no statistical difference in the protein expression was observed between leukoplakias and OSCCs (p = 0.3364, Student’s t test). The results represent the mean ± SD.
