Figure 2. The activation of FiRE in vivo in mucosal wounds occurs more rapidly than in cutaneous wounds. (A) In mucosal wounds, FiRE activity detected by X-Gal staining (blue) is most intense at 24 hours after wounding occurs. (B) In cutaneous wounds, FiRE activity is first detected at 24 hours post-wounding. (C) Three days after wounding occurs, FiRE has disappeared from mucosal wounds but (D) is still robust in cutaneous wounds.

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