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Figure 2. Task design and brain activities. (A) Experimental design of the tongue-movement paradigm indicating the alternation of "rest" and tongue-movement tasks. See text for details. (B) Projections of the activation foci on the lateral surface of a standard human brain atlas during tongue movements (i.e., TP, TR, and TL) revealed by a random-effect analysis. a, TP-"rest"; b, TR-"rest"; c, TL-"rest". Significant activations (p < 0.001 uncorrected for multiple comparisons) of bilateral S1/M1 cortices are shown. Note that there were no marked differences in activation foci for the 3 different tongue movements in terms of size or location. (C) Representative activation patterns in the S1/M1 of subjects with evident chewing-side preferences on the given sectional planes (z = 30). a, subject with a chewing-side preference exclusively on the left. b, subject with a chewing-side preference exclusively on the right. Activations of bilateral S1/M1 cortices that were significant (p < 0.05 corrected) are shown. Color code denotes T-values. Abbreviations: Tp, tongue protrusion; TR, tongue movement to the right; TL, tongue movement to the left; R, right side.
