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J DENT RES, Vol. 81, No. 1,
23-27 (2002)
DOI: 10.1177/154405910208100106
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Figure 2. Effects of IL-1 on the activation of proMMP-2 in odontogenic keratocyst fibroblasts cultured on type I collagen-coated dish. Fibroblasts were cultured in serum-free DMEM in the absence (0) or presence of various concentrations of rhIL-1 (0.01-10 nM) on plastic plates ( ) or 30 µg/cm2 type I collagen-coated dishes () for 48 hrs at 37°C. Activity ratio of MMP-2 was calculated as described under "MATERIALS & METHODS". Vertical bars indicate mean ± SE (n = 4). *p < 0.05 compared with the value of the cells grown on type I collagen-coated dishes without rhIL-1 .
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