HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via ISI Web of Science (2) Citing Articles via Google Scholar Google Scholar Articles by Shimomoto, Y. Articles by Soma, K. Search for Related Content PubMed PubMed Citation Articles by Shimomoto, Y. Articles by Soma, K.

Effects of Occlusal Stimuli on Alveolar/Jaw Bone Formation

Orthodontic Science, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan;

View larger version (20K): [in this window] [in a new window]   Figure 1. Experimental methods and mean body weight throughout the course of the experiement. (a) In the hypofunction/recovered occlusal function group, removable appliances were attached to induce occlusal hypofunction. (b) After 2 wks of occlusal hypofunction, the appliances were removed for recovered occlusal function. Untreated rats, 5–9 wks old, served as the control group. (c) Weight changes during the experimental period were similar in both groups. (d) Schematic drawing of observation regions for dynamic bone histomorphometry. The periosteal surfaces were delimited into 4 areas as alveolar crest (region 1), alveolar bone (region 2), buccal surface of the jaw bone (region 3), and inferior border of the jaw bone (region 4).

View larger version (26K): [in this window] [in a new window]   Figure 2. Frontal sections of the mandibular second molar area. (a) Control; (b) hypofunction/recovered occlusal function. Fluorescent labeling at different time points (inner yellow, 0 wk; red, 1 wk; yellow, 2 wks; red, 3 wks; yellow, 4 wks) on the periosteal surface indicates new bone formation.

View larger version (25K): [in this window] [in a new window]   Figure 3. The changes in mineral apposition rate (MAR) and bone formation rate (BFR/BS) after 2 wks of occlusal hypofunction and 2 wks of recovered occlusal function of the alveolar bone. (a,c) Alveolar crest (region 1, upper 1/2 of the tooth root, near the tooth crown). (b,d) Alveolar bone (region 2, lower 1/2 of the tooth root, near the root apex). The data are expressed as means ± SD. N = 5 for each group. *Significantly different from controls, with p < 0.05.

View larger version (25K): [in this window] [in a new window]   Figure 4. The changes in mineral apposition rate and bone formation rate after 2 wks of occlusal hypofunction and 2 wks of recovered occlusal function of the jaw bone. (a,c) Buccal surface of the jaw bone (region 3). (b,d) Inferior border of the jaw bone (region 4). The data are expressed as means ± SD. N = 5 for each group. *Significantly different from controls, with p < 0.05.