Preventive Intervention Possibilities in Radiotherapy- and Chemotherapy-induced Oral Mucositis: Results of Meta-analyses
M.A. Stokman1,*,
F.K.L. Spijkervet1,
H.M. Boezen2,
J.P. Schouten2,
J.L.N. Roodenburg1, and
E.G.E. de Vries3
1 Departments of Oral and Maxillofacial Surgery,
2 Epidemiology and Statistics, and
3 Medical Oncology, University of Groningen and University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands

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Figure 1. The development of mucositis in a 5-stage model (adapted from Sonis [2004]) and possible pathways of intervention for mucositis prevention.
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Figure 2. Standard meta-analysis plot results of PTA for the outcome "presence of ulceration".
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Figure 3. Standard meta-analysis plot results of GM-CSF/G-CSF (systemic administration) for the outcome "presence of mucositis".
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Figure 4. Standard meta-analysis plot results of oral cooling for the outcome "presence of mucositis".
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Figure 5. Standard meta-analysis plot results of amifostine for the outcome "presence of grade 3 and grade 4 mucositis".
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