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Parotid Secretory Granules: Crossroads of Secretory Pathways and Protein Storage

S.-U. Gorr, S.G. Venkatesh, and D.S. Darling*

Department of Periodontics, Endodontics and Dental Hygiene and Center for Oral Health and Systemic Disease, University of Louisville School of Dentistry, Louisville, KY 40292, USA;



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Figure. Secretory pathways in parotid acinar cells. The main organelles of the secretory pathway are labeled. TGN, trans-Golgi network; IM, immature secretory granule; SG, mature secretory granules; CL, constitutive-like secretory vesicle; mR, minor regulated pathway vesicle. The vesicular transport pathways discussed in the text are indicated by numbered arrows: (1) major regulated secretory pathway, (2) minor regulated secretory pathway, (3) apical constitutive secretory pathway, (4) constitutive-like secretory pathway, (5) basolateral constitutive secretory pathway, (6) basolateral secretion of secretory granules, and (7) alternate basolateral constitutive secretory pathway.

 





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