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Impaired Cytotoxicity in Papillon-Lefèvre Syndrome

¹ King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia;
² current address, Department of Periodontics, Loma Linda University, 24860 Taylor Street, Loma Linda, CA 92354, USA;
³ University of Kristianstad, Kristianstad, Sweden; and
⁴ Section of Periodontology, College of Dentistry, The Ohio State University, Columbus, OH, USA;

View larger version (12K): [in a new window]   Figure 1. NK cell cytotoxicity against K562 cells in PLS patients and healthy controls (mean ± SD; n = 20 for all data points except the 12.5:1 effector:target ratio, where n = 16 for both PLS and controls). *Significantly different from control (p < 0.001).

View larger version (19K): [in a new window]   Figure 2. NK cell cytotoxicity against K562 cells in PLS patients, grouped by family, and healthy controls (mean values).