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Vesiculo-erosive Oral Mucosal Disease—Management with Topical Corticosteroids: (1) Fundamental Principles and Specific Agents Available

¹ Professor of Oral Medicine, Departamento de Medicina Oral, Facultad de Odontología, Universidad de Granada, Campus de Cartuja sn, 18071, Granada, Spain; and
² Dean and Director of Studies and Research, Eastman Dental Institute for Oral Health Care Sciences, University College London, University of London, UK;

View larger version (64K): [in a new window]   Figure 1. Result of treatment of major aphthous ulcers. (A) Patient with major aphthous ulcers that completely responded (B) to treatment with an aqueous solution of 0.005% clobetasol propionate + 100,000 IU/cc nystatin.

View larger version (63K): [in a new window]   Figure 2. Result of treatment of mucous membrane pemphigoid. (A) Patient with gingival ulcerations as severe expression of mucous membrane pemphigoid that completely responded (B) to the use of 0.05% clobetasol propionate + 100,000 IU/cc nystatin in orabase paste applied with a tailor-made tray. A certain degree of gingival atrophy persists.