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Magnesium Deficiency is Associated with Periodontal Disease

P. Meisel1,*, C. Schwahn2, J. Luedemann3, U. John4, H.K. Kroemer1, and T. Kocher2

1 Department of Pharmacology, 2 Dental Clinics, Unit of Periodontology, 3 Department of Clinical Chemistry and Laboratory Medicine, and 4 Institute of Epidemiology, Ernst Moritz Arndt University, F.-Loeffler-Str. 23d, D-17487 Greifswald, Germany;



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Figure. Periodontal parameters in subjects with low and high Mg/Ca ratios. (A) Percentage of sites having a probing depth of sites ≥ 4 mm. (B) Percentage of sites having an attachment loss ≥ 4 mm. A distinction was made between subjects in the lowest quartile (dashed) and those in the uppermost quartile (solid lines). Shown are the fitted lines, including the 95% confidence intervals (dotted lines). A non-linear regression fit to logistic equations was used. (C) Extent in percent of sites ≥ 4 mm of probing depth (left panel), of attachment loss ≥ 4 mm (mid-panel), and number of teeth (right panel), and the Mg/Ca ratio in the population study (ages 40 to 80 yrs). The Mg/Ca ratio was in the quartiles: 1, ≤ 0.298; 2, > 0.298 - ≤ 0.318; 3, > 0.318 - ≤ 0.342; and 4, > 0.342. Given are the means and 95% confidence intervals. Number of subjects N > 500 in each quartile. Kruskal-Wallis test: probing depth, p = 0.022; attachment loss, p = 0.489; and number of teeth, p = 0.006. Trend: probing depth, p < 0.001; attachment loss, p = 0.058; and number of teeth, p < 0.001.

 





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