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Mast Cells in Human Periodontal Disease

Oral Biology and Pathology, School of Dentistry, The University of Queensland, Brisbane 4072, Australia;

View larger version (62K): [in a new window]   Figure 1. Tryptase+ mast cells in the lesion of a biopsy from a chronic periodontitis patient with a "large" lesion (A,B). C-kit+ mast cells appearing to be in close contact with lymphocytes in a "small" lesion of a biopsy from a chronic periodontitis patient (C).

View larger version (11K): [in a new window]   Figure 2. The mean percent (± standard error of the mean) tryptase+ and c-kit+ mast cells in (A) the lesions of healthy/gingivitis (n = 22) and periodontitis (n = 31) subjects; (B) healthy/gingivitis tissues placed into 3 groups on the basis of size of infiltrate ("small", n = 9; "medium", n = 7; "large", n = 6); and (C) periodontitis lesions placed into 3 groups on the basis of size of infiltrate ("small", n = 8; "medium", n = 12; "large", n = 11).

View larger version (11K): [in a new window]   Figure 3. The mean percent (± standard error of the mean) IgG2+ and IgG4+ B-cells/plasma cells in (A) the lesions of healthy/gingivitis (n = 21) and periodontitis (n = 29) subjects; (B) healthy/gingivitis tissues placed into 3 groups on the basis of size of infiltrate ("small", n = 9; "medium", n = 6; "large", n = 6); and (C) periodontitis lesions placed into 3 groups on the basis of size of infiltrate ("small", n = 7; "medium", n = 12; "large", n = 10).