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Periodontitis and Systemic Inflammation: Control of the Local Infection is Associated with a Reduction in Serum Inflammatory Markers

¹ Department of Periodontology, Eastman Dental Institute and Hospital, University College London, 256 Gray’s Inn Road, London WC1X 8LD, UK;
² Eastman Clinical Investigation Center, Eastman Dental Institute and Hospital, University College London; and
³ Microbiology Unit, Eastman Dental Hospital, University College London Hospitals, NHS Trust;

View larger version (13K): [in a new window]   Figure 1. Box-and-whiskers plots showing CRP serum levels before and 2 and 6 mos following treatment of periodontitis (N = 94). The box refers to the 25th (bottom) and 75th (up) percentiles, and the median is the horizontal line inside. P < 0.0001 Wilcoxon rank-sum paired test compared with baseline.

View larger version (11K): [in a new window]   Figure 2. Box-and-whiskers plots showing IL-6 serum levels before and 2 and 6 mos following treatment of periodontitis (N = 94). P = 0.021 and P = 0.006 Wilcoxon rank-sum paired test compared with baseline.