This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Shinagawa, H. Articles by Ohyama, K. Search for Related Content PubMed PubMed Citation Social Bookmarking                   What's this?

Chewing-side Preference is Involved in Differential Cortical Activation Patterns during Tongue Movements after Bilateral Gum-chewing: a Functional Magnetic Resonance Imaging Study

¹ Maxillofacial Orthognathics, ² Oral/Maxillofacial Radiology, and ³ Cognitive Neurobiology, Graduate School, Tokyo Medical and Dental University, 5-45 Yushima 1-chome, Bunkyo-Ku, Tokyo 113-8549, Japan; ⁴ Department of Physiology, Nihon University, School of Medicine, Tokyo 113-8610, Japan; ⁵ Tokyo Metropolitan Institute of Gerontology, Tokyo 173-0015; and ⁶ Department of Oral/Maxillofacial Radiology, The University of Tokushima, Tokushima 770-8503, Japan;

View larger version (38K): [in this window] [in a new window]   Figure 1. (A) A representative coronal projection of mandibular movement in a subject, which was recorded with the use of a mandibular kinesiograph. The trajectory of the open-close movement in this subject shows a slight deviation to the right at the maximum gape (Aa). When the subject chewed gum without any instruction, the jaw trajectory shows a marked deviation to the left, indicating a strong left chewing-side preference (Ab). When the subject was instructed to chew the gum bilaterally, the laterality of the jaw trajectory disappeared (Ac). Green lines and downward arrows indicate jaw-opening trajectories, while red lines and upward arrows indicate jaw-closing trajectories. Several cycles are superimposed. L indicates the left side. Bars denote 5 mm. (B) Block design of the tongue movement paradigm.

View larger version (68K): [in this window] [in a new window]   Figure 2. Projections of the activation foci on the lateral aspect of the standard human brain during tongue protrusion and rightward and leftward tongue movements (n = 6). Activations of bilateral sensorimotor cortices that were statistically significant (p < 0.05 corrected for multiple comparisons) are shown. Color code denotes T-values. Abbreviations for Figs. 2 and 3: TP, tongue protrusion; TR, rightward tongue movement; TL, leftward tongue movement; Before, before gum-chewing; After1st, the first 10-minute period beginning immediately after gum-chewing; After2nd, the second 10-minute period from 10 min to 20 min after gum-chewing.

View larger version (13K): [in this window] [in a new window]   Figure 3. Comparisons of the mean change in the BOLD signal in both the right and left primary sensorimotor cortices during tongue protrusion (TP) and rightward (TR) and leftward (TL) tongue movements (n = 6). Solid bars indicate standard errors of the mean. F values along with P values by repeated two-way ANOVA, as well as means and standard errors of the mean, are indicated. **p < 0.01.

CiteULike

Connotea

Del.icio.us

Digg

Reddit

Technorati