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New Bacterial Species Associated with Chronic Periodontitis

P.S. Kumar1, A.L. Griffen2,*, J.A. Barton3, B.J. Paster4,5, M.L. Moeschberger6, and E.J. Leys7

1 Department of Periodontology,
2 Department of Pediatric Dentistry,
3 College of Dentistry,
7 Department of Oral Biology, College of Dentistry, and
6 Division of Epidemiology and Biometrics, School of Public Health, College of Medicine and Public Health, The Ohio State University, 305 W. 12th Ave., PO Box 182357, Columbus, OH 43218-2357;
4 Department of Molecular Genetics, The Forsyth Institute, and
5 Department of Oral and Developmental Biology, Harvard School of Dental Medicine, Boston, MA;



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Figure 1. Prevalence of 39 bacterial species or phylotypes in 66 subjects with periodontitis and 66 healthy control subjects. Differences significant by chi-square analysis with P < 0.05 are marked "*" after the species name; differences significant with P < 0.002 are marked "**".

 


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Figure 2. Prevalence ratios (calculated like a relative risk) for 39 bacterial species or phylotypes for 66 subjects with periodontitis and 66 healthy control subjects. Ninety-five percent confidence intervals are shown as bars. The values to the left of 1 show species more common in health than in disease, and those to the right of 1 show species more common in disease than in health. Confidence intervals could not be calculated for F. nucleatum or G. morbillorum, since there were 0 subjects without the bacteria in the disease group.

 





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