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Genetic Mapping of the Absence of Third Molars in EL Mice to Chromosome 3

¹ Department of Pediatric Dentistry, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-Nishi, Matsudo, Chiba 271-8587, Japan; and
² Department of Pediatric Dentistry, Tsurumi University School of Dentistry, 2-1-3 Tsurumi, Tsurumi-ku, Yokohama 230-8501, Japan;

View larger version (24K): [in this window] [in a new window]   Figure. Linkage analysis of chromosome 3 (A) and chromosome 16 (B). Genotype in 15 F2 mice with absence of M3 (I), in 15 F2 mice with normal dentition (II), and in 7 N2 mice with absence of M3 (III). Filled squares denote homozygosity for the EL allele; open squares denote homozygosity for the MSM allele; stippled squares denote heterozygosity for the EL/MSM allele; blank indicates that the marker was not tested. 2 values for genotyping ratio of F2 at each marker are shown to the right of the genotype panel; ap < 0.05; bp < 0.01; cp < 0.001; dp < 0.0005; ep < 0.0001. An illustration of the map position of the Mit markers in centimorgans (cM) from the centromere, relative to potential candidate genes, placed according to the Mouse Genome Database (MGD).

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