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Fourier Analysis Reveals Increased Trabecular Spacing in Sickle Cell Anemia

Section of Oral and Maxillofacial Radiology, UCLA School of Dentistry, 10833 Le Conte Ave., Los Angeles, CA 90095-1668, USA;

View larger version (59K): [in this window] [in a new window]   Figure 1. Intertrabecular spacing. (A) Fourier frequency distribution for an individual with sickle cell anemia. The peak frequency (large arrow) is 1.28 trabeculae per mm, corresponding to an intertrabecular spacing of 0.78 mm. The widths (stippled) and means (horizontal bar) of the low- and high-frequency bands used to compute the ratio metric. (B) Processed image where trabeculae are white, showing a 0.78-mm line in white in comparison with intertrabecular spaces.

View larger version (27K): [in this window] [in a new window]   Figure 2. Distribution of trabeculae per mm, comparing sickle cell anemia (SCA) individuals (dashed line) and controls (solid line) for the mesio-distal analysis direction in the mandible. Individuals with sickle cell anemia have more low-frequency components (large intertrabecular spacing) and fewer high-frequency components (small intertrabecular spacing) than control individuals. Note crossover in frequency distributions at 2 trabeculae per mm.

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