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Is Reduction of Pocket Probing Depth Correlated with the Baseline Value or is it "Mathematical Coupling"?

Y.-K. Tu1, M.S. Gilthorpe1,*, and G.S. Griffiths2

1 Biostatistics Unit, Academic Unit of Epidemiology and Health Services Research, Medical School, University of Leeds, 24 Hyde Terrace, Leeds, LS2 9LN, UK; and
2 Department of Periodontology, Eastman Dental Institute, University College London, 256 Gray’s Inn Road, London, WC1X 8LD, UK;




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Figure 1. An illustration of mathematical coupling (MC) without any effect of regression to the mean (RTM). (A) True Y values plotted against true X values, with no underlying relationship between them. (B) A spurious correlation between true Z (= X - Y) and true X is shown; the solid line is the regression of Z on X; this represents the hypothetical situation of MC without RTM.

 



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Figure 2. An illustration of mathematical coupling (MC) due entirely to the effect of regression to the mean (RTM). (A) Observed y values plotted against observed x values, with the underlying relationship between them represented by the solid line. (B) A spurious correlation between z (= x - y) and x is shown; the solid line is the regression of z on x; this represents the hypothetical situation of MC as entirely RTM.

 





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