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Journal of Dental Research, Vol. 81, No. 10,
716-721 (2002)
DOI: 10.1177/154405910208101012
Amplified Crevicular Leukocyte Activity in Aggressive Periodontal Disease
R. Buchmann1,*,
A. Hasilik2,
T.E. Van Dyke1 and
D.E. Lange3
1 Department of Periodontology and Oral Biology, Goldman School of Dental Medicine, Boston University, Boston, MA, USA;
2 Institute of Physiological Chemistry, University of Marburg, Germany; and
3 Department of Periodontology, School of Dental Medicine, University of Münster, Germany;

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Figure. Initial GCF neutrophil responses in AP were significantly amplified compared with those in CP. (A) Myeloperoxidase activity (MPO); (B) beta-N-acetyl-hexosaminidase activity (Beta-NAH); (C) cathepsin D (CD); and (D) elastase-alpha-1-proteinase inhibitor complex (Alpha-1-EPI). PRE = outset. 6 M = 6 mos post-therapy. The post-treatment levels remained significantly different between AP and CP (not CD and Alpha-1-EPI).
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