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1 University of Illinois, Colleges of Medicine and Dentistry, and the State Department of Public Health, Chicago, Illinois
Intra-intestinal chemical and bacteriological changes can take place as a result of systemic intoxication due to oral septic lesions. These changes are brought about by damage to parenchymal tissue in the gastro-intestinal tract. The diminution in acid secretion by the stomach tends to upset the normal acid-base balance of the contents of the upper half of the small intestine. This is accompanied by an ascension upward of fecal bacterial flora into the jejunum and duodenum. The alterations in inorganic salt metabolism, and the absorption of by-products of disintegrated B. coli proteins, have been emphasized.
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