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1 Columbia University Dental School, New York, N. Y.
2 Berlin, Germany
(1) Enamel is destroyed during dental caries by two agencies: (a) by acid, in all probability lactic acid, formed by B. acidophilus, and (b) by the proteolytic action of bacteria (streptococci or diplococci?) upon a portion of the protein content.
(2) The selectivity shown by the proteolytic bacteria, in destroying the content of the enamel rod more quickly than the enclosing enamelrod sheath, suggests that these two structures differ chemically. The authors believe the sheath is composed of keratin and the rod proper of calcified protoplasm (albumin; albumin-like material).
(3) If this theory is correct, it suggests that the enamel is developed embryonically by the direct calcification of the enamel-forming cells, the ameloblasts, and that the enamel is therefore a calcified tissue.
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